AC T02319
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ID T02319
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DT 10.12.1997 (created); ili.
DT 12.12.2008 (updated); pum.
CO Copyright (C), QIAGEN.
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FA AML3-U1
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SY CBFA1; PEBP2alphaA; til-1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G005054 Runx2.
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CL C0029; runt.
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SZ 360 AA; 39.3 kDa (cDNA) (calc.).
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SQ MASNSLFSAVTPCQQSFFWDPSTSRRFSPPSSSLQPGKMSDVSPVVAAQQQQQQQQQQQQ
SQ QQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAAVPRLRPPHDNRTMVEIIADHPAEL
SQ VRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENYSAELRNASA
SQ VMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRRHRQK
SQ LDDSKPSLFSDRLSDLGRIPHPSMRVGVPPQNPRPSLNSAPSPFNPQGQSQITDPRQAQS
SQ SPPWSYDQSYPSYLSQMTSPSIHSTTPLSSTRGTGLPAITDVPRRISGFCGTTTTTTTKL
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SC edited EMBL #AF005936
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FT 15 247 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 106 240 
PF00853; Runt domain.
FT 108 236 
PS51062; RUNT.
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SF minor isoform of PEBP2alphaA expressed in murine lymphoma with proviral insertions at til-1 locus [1];
SF other structurally different minor isoforms in these cells are (Y1/2) T02320 [1];
SF major isoform expressed in these cells is (G1) T02318 [1];
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CP osteosarcoma, lymphoma and osteoblast cell lines [1].
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MX M07276 V$AML3_Q3.
MX M08866 V$AML_Q4.
MX M00769 V$AML_Q6.
MX M00731 V$OSF2_Q6.
MX M00984 V$PEBP_Q6.
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DR TRANSPATH: MO000026316.
DR EMBL: AF005936;
DR UniProtKB: Q08775-7; RUNX2_MOUSE.
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RN [1]; RE0006487.
RX PUBMED: 9238031.
RA Stewart M., Terry A., Hu M., O'Hara M., Blyth K., Baxter E., Cameron E., Onions D. E., Neil J. C.
RT Proviral insertions induce the expression of bone-specific isoforms of PEBP2alphaA (CBFA1): Evidence for a new myc collaborating oncogene
RL Proc. Natl. Acad. Sci. USA 94:8646-8651 (1997).
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//