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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T02374 XX ID T02374 XX DT 01.04.1998 (created); ili. DT 12.01.2011 (updated); din. CO Copyright (C), QIAGEN. XX FA Rb XX OS monkey, Cercopithecus aethiops OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates; haplorhini; catarrhini; cercopithecidae; cercopithecinae XX SF phosphorylation of Rb is cell cycle-dependent: Rb is unphosphorylated in G0/G1, gets phosphorylated at the beginning of S and remains phosphorylated until the end of G2 [4] [5]; SF only unphosphorylated Rb can be found complexed with SV40 T-Ag [3] [5]; XX IN T00788 T-Ag; SV40, simian virus 40. XX BS R04915. XX DR TRANSPATH: MO000026364. XX RN [1]; RE0006713. RX PUBMED: 8007947. RA Chen L. I., Nishinaka T., Kwan K., Kitabayashi I., Yokoyama K., Fu Y.-H. F., Gruenwald S., Chiu R. RT The retinoblastoma gene product RB stimulates Sp1-mediated transcription by liberating Sp1 from a negative regulator RL Mol. Cell. Biol. 14:4380-4389 (1994). RN [2]; RE0013304. RX PUBMED: 2839300. RA DeCaprio J. A., Ludlow J. W., Figge J., Shew J.-Y., Huang C.-M., Lee W.-H., Marsilio E., Paucha E., Livingston D. M. RT SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. RL Cell 54:275-283 (1988). RN [3]; RE0013305. RX PUBMED: 2910497. RA Ludlow J. W., DeCaprio J. A., Huang C.-M., Lee W.-H., Paucha E., Livingston D. M. RT SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family. RL Cell 56:57-65 (1989). RN [4]; RE0013306. RX PUBMED: 2673542. RA DeCaprio J. A., Ludlow J. W., Lynch D., Furukawa Y., Griffin J., Piwnica-Worms H., Huang C.-M., Livingston D. M. RT The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. RL Cell 58:1085-1095 (1989). RN [5]; RE0013307. RX PUBMED: 2154332. RA Ludlow J. W., Shon J., Pipas J. M., Livingston D. M., DeCaprio J. A. RT The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. RL Cell 60:387-396 (1990). XX //