AC T02375
XX
ID T02375
XX
DT 01.04.1998 (created); ili.
CO Copyright (C), QIAGEN.
XX
FA NS-1
XX
OS MVM(p), minute virus of mice
OC viridae; ss-DNA nonenveloped viruses; parvoviridae; parvovirus
XX
SZ 672 AA; 76.2 kDa (cDNA) (calc.), 83 kDa [1]
XX
SQ MAGNAYSDEVLGATNWLKEKSNQEVFSFVFKNENVQLNGKDIGWNSYKKELQEDELKSLQ
SQ RGAETTWDQSEDMEWETTVDEMTKKQVFIFDSLVKKCLFEVLNTKNIFPGDVNWFVQHEW
SQ GKDQGWHCHVLIGGKDFSQAQGKWWRRQLNVYWSRWLVTACNVQLTPAERIKLREIAEDN
SQ EWVTLLTYKHKQTKKDYTKCVLFGNMIAYYFLTKKKISTSPPRDGGYFLSSDSGWKTNFL
SQ KEGERHLVSKLYTDDMRPETVETTVTTAQETKRGRIQTKKEVSIKTTLKELVHKRVTSPE
SQ DWMMMQPDSYIEMMAQPGGENLLKNTLEICTLTLARTKTAFDLILEKAETSKLTNFSLPD
SQ TRTCRIFAFHGWNYVKVCHAICCVLNRQGGKRNTVLFHGPASTGKSIIAQAIAQAVGNVG
SQ CYNAANVNFPFNDCTNKNLIWVEEAGNFGQQVNQFKAICSGQTIRIDQKGKGSKQIEPTP
SQ VIMTTNENITVVRIGCEERPEHTQPIRDRMLNIHLTHTLPGDFGLVDKNEWPMICAWLVK
SQ NGYQSTMASYCAKWGKVPDWSENWAEPKVPTPINLLGSARSPFTTPKSTPLSQNYALTPL
SQ ASDLEDLALEPWSTPNTPVAGTAETQNTGEAGSKACQDGQLSPTWSEIEEDLRACFGAEP
SQ LKKDFSEPLNLD
XX
SC Swiss-Prot#P03134
XX
FT 184 505 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 269 550 
PF01057; Parvovirus non-structural protein NS1.
FT 591 672 
activation domain [1].
XX
SF nuclear phosphoprotein [1];
SF 2 potential acidic domains [1];
XX
FF does not bind DNA in a sequence specific manner [1];
FF interact with Sp1 to activate transcription from the SV40 promoter in Schneider 2 cells [1];
XX
IN T00759 Sp1; human, Homo sapiens.
XX
DR TRANSPATH: MO000026365.
DR UniProtKB: P03134;
XX
RN [1]; RE0006743.
RX PUBMED: 7799962.
RA Krady J. K., Ward D. C.
RT Transcriptional activation by the parvoviral nonstructural protein NS-1 is mediated via a direct interaction with Sp1
RL Mol. Cell. Biol. 15:524-533 (1995).
XX
//