AC T02377
AS T09581.
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ID T02377
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DT 03.04.1998 (created); ewi.
DT 07.06.2012 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA USF2b
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SY FIP; Fos-interacting protein; Major late transcription factor 2; MLTF; MLTFI; UEF; upstream stimulatory factor 2; upstream stimulatory factor 2b; upstream transcription factor 1; upstream transcription factor 2; USF1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002993 USF2; HGNC: USF2.
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CL C0012; bHLH-ZIP.
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SZ 279 AA; 30.6 kDa (cDNA) (calc.).
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SQ MDMLDPGLDPAASATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAITSVQQAAFG
SQ DHNIQYQFRTETNGGQAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTD
SQ QSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRR
SQ RDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERL
SQ QMDNELLRQQIEELKNENALLRAQLQQHNLEMVGEGTRQ
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SC edited Swiss-Prot #Q15853
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FT 126 152 USF-specific conserved region [1].
FT 167 224 PS50888; HLH.
FT 169 224 PF00010; Helix-loop-helix DNA-binding domain.
FT 174 229 SM00353; finulus.
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SF alternative splice variant is USF2 T00878;
SF preferentially heterodimerizes with USF (USF1) [2];
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CP ubiquitous.
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FF weak activator [2];
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IN T00874 USF1; human, Homo sapiens.
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MX M01034 V$EBOX_Q6_01.
MX M07067 V$USF1_Q4.
MX M00726 V$USF2_Q6.
MX M03860 V$USF2_Q6_01.
MX M00187 V$USF_Q6.
MX M00796 V$USF_Q6_01.
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BS R00992.
BS R00336.
BS R04408.
BS R04419.
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DR TRANSPATH: MO000026367.
DR EMBL: X90825;
DR UniProtKB: Q15853-3; USF2_HUMAN.
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RN [1]; RE0003428.
RX PUBMED: 1450663.
RA Sirito M., Walker S., Lin Q., Kozlowski M. T., Klein W. H., Sawadogo M.
RT Members of the USF family of helix-loop-helix proteins bind DNA as homo- as well as heterodimers
RL Gene Expr. 2:231-240 (1992).
RN [2]; RE0006753.
RX PUBMED: 8576131.
RA Viollet B., Lefrancois-Martinez A. M., Henrion A., Kahn A., Raymondjean M., Martinez A.
RT Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms
RL J. Biol. Chem. 271:1405-1415 (1996).
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