AC T02386
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ID T02386
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DT 07.04.1998 (created); ewi.
DT 07.06.2010 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA L-Myc-1(short form)
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004699 MYCL; HGNC: MYCL.
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CL C0012; bHLH-ZIP; 1.2.6.5.3.2.
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SZ 206 AA; 21.8 kDa (gene) (calc.).
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SQ MDYDSYQHYFYDYDCGEDFYRSTAPSEDIWKKFELVPSPPTSPPWGLGPGAGDPAPGIGP
SQ PEPWPGGCTGDEAESRGHSKGWGRNYASIIRRDCMWSGFSARERLERAVSDRLAPGAPRG
SQ NPPKASAAPDCTPSLEAGNPAPAAPCPLGEPKTQACSGSESPSDSGKDLPEPSKRGPPHG
SQ WPKLCPCLRSGIGSSQALGPSPPLFG
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SC SPTREMBL #Q14897
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FT 1 202 PF01056; Myc amino-terminal region.
FT 166 206 replaced by 166-364 in L-Myc (long form) [2].
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SF alternative splice product is L-Myc (long form) lacking the whole DNA-binding bHLH-ZIP domain T02385;
SF the short form only comprises the trans-activation domain of L-Myc [1];
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CP placenta [2].
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FF unknown function;
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DR TRANSPATH: MO000026376.
DR EMBL: M19720;
DR UniProtKB: P12524-2;
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RN [1]; RE0003207.
RX PUBMED: 1620120.
RA Barrett J., Birrer M. J., Kato G. J., Dosaka-Akita H., Dang C. V.
RT Activation domains of L-Myc and c-Myc determine their transforming potencies in rat embryo cells
RL Mol. Cell. Biol. 12:3130-3137 (1992).
RN [2]; RE0006779.
RX PUBMED: 2827002.
RA Kaye F., Battey J., Nau M., Brooks B., Seifter E., de Greve J., Birrer M., Sausville E., Minna J.
RT Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing
RL Mol. Cell. Biol. 8:186-195 (1988).
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