AC T02388
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ID T02388
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DT 07.04.1998 (created); ewi.
CO Copyright (C), QIAGEN.
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FA L-Myc-1
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OS clawed frog, Xenopus laevis
OC eukaryota; animalia; metazoa; chordata; vertebrata; amphibia; lissamphibia; anura; archeobatrachia; pipoidea; pipidae
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CL C0012; bHLH-ZIP.
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SZ 344 AA; 38.4 kDa (cDNA) (calc.).
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SQ MDVGSCNNHYFYDVDMKEDFYRCIAPSEDIWKKFELVPGFPLSPGGCPGGGGTDWGAELM
SQ DLGWESPMKLTGLSSVVLLRDCMWSGFSTRERLEKVIHERLTTASPRATNPQKPVADHEN
SQ SEPGVNSIEQNATPLVVPTPVPEKVPNSSGSESTSDSEDDEIDVVTIEKRKSYGGRQPVT
SQ ITVRADPTATKLFHISIHQQQHNYAARLPPEPNSMSPQPNFHSPIKEEPGEVTSPPALQQ
SQ CSSPMPGSPLASGSSDSEDIVKKKNHNYLERKRRNDLRSRFLALREEVPSLTRSTKTPKV
SQ VVLSKATEFLKGLVIQEQQLTAERFKLWSRHQQLLRRISHLKGR
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SC Swiss-Prot#Q05404
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FT 1 244 
PF01056; Myc amino-terminal region.
FT 262 314 
PF00010; Helix-loop-helix DNA-binding domain.
FT 262 314 
PS50888; HLH.
FT 267 319 
SM00353; finulus.
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SF efficient DNA binding requires dimerization with another bHLH protein;
SF binds DNA as an heterodimer with Max [1];
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CP (embryos:) fertilized egg, blastula; (adult:) oocytes, kidney [1].
CN CNS, eye, gall bladder, heart, intestine, liver, lung, muscle, reproductive tract, skin, spleen [1].
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FF no transformation capability [1];
FF coordinate expression with L-Myc-2 [1];
FF high expression rate contrasts with that of mammals and has been attributed to the high regenerative capacity of amphibian tissues [1];
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IN T00489 Max-isoform2; human, Homo sapiens.
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DR TRANSPATH: MO000026378.
DR EMBL: L11362;
DR UniProtKB: Q05404;
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RN [1]; RE0006772.
RX PUBMED: 8455622.
RA Schreiber-Agus N., Torres R., Horner J., Lau A., Jamrich M., DePinho R. A.
RT Comparative analysis of the expression and oncogenic activities of Xenopus c-, N-, and L-myc homologs
RL Mol. Cell. Biol. 13:2456-2468 (1993).
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