AC T02399
XX
ID T02399
XX
DT 08.04.1998 (created); ili.
CO Copyright (C), QIAGEN.
XX
FA Vpr
XX
OS HIV-1, human immunodeficiency virus type 1
OC viridae; ss-RNA enveloped viruses; positive strand RNA viruses; retroviridae; lentivirinae
XX
SZ 96 AA; 11.4 kDa (cDNA) (calc.).
XX
SQ MEQAPEDQGPQREPYNDWTLELLEELKNEAVRHFPRIWLHSLGQHIYETYGDTWTGVEAL
SQ IRILQQLLFIHFRIGCRHSRIGIIQQRRTRNGASKS
XX
SC Swiss-Prot#Q73369
XX
FT 1 83 
PF00522; VPR/VPX protein.
XX
FF trans-activates HIV-1 LTR through interaction with Sp1 only when Sp1 is bound to multiple sites within this LTR [1];
FF localize in the nucleus [1];
FF accessory regulatory protein [1];
FF activates HIV-1 replication in latently infected cells [1];
XX
IN T00759 Sp1; human, Homo sapiens.
XX
BS R00704.
XX
DR TRANSPATH: MO000026389.
DR EMBL: U39362;
DR UniProtKB: Q73369;
XX
RN [1]; RE0006790.
RX PUBMED: 7592727.
RA Wang L., Mukherjee S., Jia F., Narayan O., Zhao L.-J.
RT Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat
RL J. Biol. Chem. 270:25564-25569 (1995).
XX
//