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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T02399 XX ID T02399 XX DT 08.04.1998 (created); ili. CO Copyright (C), QIAGEN. XX FA Vpr XX OS HIV-1, human immunodeficiency virus type 1 OC viridae; ss-RNA enveloped viruses; positive strand RNA viruses; retroviridae; lentivirinae XX SZ 96 AA; 11.4 kDa (cDNA) (calc.). XX SQ MEQAPEDQGPQREPYNDWTLELLEELKNEAVRHFPRIWLHSLGQHIYETYGDTWTGVEAL SQ IRILQQLLFIHFRIGCRHSRIGIIQQRRTRNGASKS XX SC Swiss-Prot#Q73369 XX FT 1 83 PF00522; VPR/VPX protein. XX FF trans-activates HIV-1 LTR through interaction with Sp1 only when Sp1 is bound to multiple sites within this LTR [1]; FF localize in the nucleus [1]; FF accessory regulatory protein [1]; FF activates HIV-1 replication in latently infected cells [1]; XX IN T00759 Sp1; human, Homo sapiens. XX BS R00704. XX DR TRANSPATH: MO000026389. DR EMBL: U39362; DR UniProtKB: Q73369; XX RN [1]; RE0006790. RX PUBMED: 7592727. RA Wang L., Mukherjee S., Jia F., Narayan O., Zhao L.-J. RT Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat RL J. Biol. Chem. 270:25564-25569 (1995). XX //