AC T02466
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ID T02466
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DT 08.06.1998 (created); ewi.
DT 10.02.2011 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA AP-2alphaB
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SY activator protein 2B.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002615 TFAP2A; HGNC: TFAP2A.
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CL C0032; bHSH; 1.3.1.0.1.2.
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SZ 365 AA; 40.6 kDa (cDNA) (calc.).
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SQ MLWKLTDNIKYEDCEDRHDGTSNGTARLPQLGTVGQSPYTSAPPLSHTPNADFQPPYFPP
SQ PYQPIYPQSQDPYSHVNDPYSLNPLHAQPQPQHPGWPGQRQSQESGLLHTHRGLPHQLSG
SQ LDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPV
SQ SLSKSNSNAVSAIPINKDNLFGGVVNPNEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSP
SQ PECLNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAANVTLLTSLVEGKRIHL
SQ LTRRNFLLGKWIIFSGQMFGRILCQLGSFIFAENIARCEWNYFMAKRNICMYSYTSILLP
SQ SFPLP
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SC SPTREMBL #Q13777
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FT 207 365 PF03299; Transcription factor AP-2.
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SF splice variant of AP-2alphaA T00035;
SF no DNA-binding due to lack of dimerization domain [1];
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CP (teratocarcinoma cell line PA-1).
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FF repressor of AP-2alphaA activity [1];
FF for repressing DNA-binding of AP-2alphaA, it requires an additional nuclear factor [1];
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MX M00469 V$AP2ALPHA_01.
MX M01045 V$AP2ALPHA_02.
MX M01047 V$AP2ALPHA_03.
MX M07348 V$AP2ALPHA_Q4.
MX M01857 V$AP2ALPHA_Q6.
MX M00800 V$AP2_Q3.
MX M08867 V$AP2_Q4.
MX M00189 V$AP2_Q6.
MX M00915 V$AP2_Q6_01.
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BS R34361.
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DR TRANSPATH: MO000026447.
DR EMBL: M61156;
DR UniProtKB: P05549-2;
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RN [1]; RE0006888.
RX PUBMED: 8321221.
RA Buettner R., Kannan P., Imhof A., Bauer R., Yim S. O., Glockshuber R., van Dyke M. W., Tainsky M. A.
RT An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2
RL Mol. Cell. Biol. 13:4174-4185 (1993).
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