TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T02513 AS T04889. XX ID T02513 XX DT 29.07.1998 (created); tme. DT 04.03.2015 (updated); hna. CO Copyright (C), QIAGEN. XX FA HNF-3beta XX SY Foxa2; hepatocyte nuclear factor 3-beta; HNF3b; TCF3b. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G013746 FOXA2; HGNC: Foxa2. XX CL C0023; fork head; XX CP (adult) bronchial epithelial (Clara) cells, liver [1]. XX FF FoxA2 and FoxD3 T04167 show an additive, not synergistic, activation of the FoxA2 promoter R16331 [3]; XX MX M00131 V$HNF3B_01. MX M02014 V$HNF3B_Q6. MX M00791 V$HNF3_Q6. MX M01012 V$HNF3_Q6_01. XX BS R25906. BS R71544. BS R66552. BS R38155. BS R38156. BS R38157. BS R38158. BS R20251. BS R26381. BS R25364. BS R55816. BS R40198. BS R21373. BS R39739. BS R19711. BS R04122. BS R25905. BS R34905. BS R41513. BS R32065. BS R04663. BS R17149. BS R17151. BS R17157. BS R57418. BS R60905. BS R21353. BS R26747. BS R34798. BS R38381. BS R26383. BS R55814. BS R55815. BS R26748. BS R04658. BS R12969. BS R12970. BS R21113. BS R55812. BS R00581. BS R26408. BS R16331. BS R26749. BS R08894. XX DR TRANSPATH: MO000026493. DR TRANSCOMPEL: C00277. DR TRANSCOMPEL: C00278. DR UniProtKB: Q9Y261; HN3B_HUMAN. XX RN [1]; RE0006956. RX PUBMED: 7755566. RA Bingle C. D., Hackett B. P., Moxley M., Longmore W., Gitlin J. D. RT Role of hepatocyte nuclear factor-3alpha and hepatocyte nuclear factor-3beta in Clara cell secretory protein expression in the bronchiolar epithelium RL Biochem. J. 308:197-202 (1995). RN [2]; RE0017167. RX PUBMED: 10672453. RA Yamada S., Zhu Q., Aihara Y., Onda H., Zhang Z., Yu L., Jin L., Si Y. J., Nishigori H., Tomura H., Inoue I., Morikawa A., Yamagata K., Hanafusa T., Matsuzawa Y., Takeda J. RT Cloning of cDNA and the gene encoding human hepatocyte nuclear factor (HNF)-3 beta and mutation screening in Japanese subjects with maturity-onset diabetes of the young RL Diabetologia 43:121-124 (2000). RN [3]; RE0025441. RX PUBMED: 11891324. RA Guo Y., Costa R., Ramsey H., Starnes T., Vance G., Robertson K., Kelley M., Reinbold R., Scholer H., Hromas R. RT The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression. RL Proc. Natl. Acad. Sci. USA 99:3663-3667 (2002). RN [4]; RE0064744. RX PUBMED: 18096723. RA Freund C., Ward-van Oostwaard D., Monshouwer-Kloots J., van den Brink S., van Rooijen M., Xu X., Zweigerdt R., Mummery C., Passier R. RT Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells. RL Stem Cells 26:724-733 (2008). RN [5]; RE0066217. RX PUBMED: 19769745. RA Pandey A. K., Bhardwaj V., Datta M. RT Tumour necrosis factor-alpha attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells. RL FEBS J. 276:3757-3769 (2009). RN [6]; RE0072582. RX PUBMED: 21856370. RA Wu Y. L., Peng X. E., Wang D., Chen W. N., Lin X. RT Human liver fatty acid binding protein (hFABP1) gene is regulated by liver-enriched transcription factors HNF3beta and C/EBPalpha. RL Biochimie 94:384-392 (2012). XX //