AC T04167
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ID T04167
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DT 09.01.2001 (created); rio.
DT 23.09.2015 (updated); hna.
CO Copyright (C), QIAGEN.
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FA HFH2
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SY forkhead box D3; FOXD3; Genesis; HFH-2; HFH2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G006087 FOXD3; HGNC: Foxd3.
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CL C0023; fork head; 3.3.1.4.3.
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CP highly expressed in embryonic stem cells [1].
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FF Oct4 T00652 inhibits almost completely the activation of the FoxA1 promoter by FoxD3 [1];
FF dose dependent activation of the FoxA1 promoter at lower levels, but at higher levels failed to activate the promoter [1];
FF FoxA1T02512 and FoxD3 show an additive, not synergistic, activation of the FoxA1 promoter R16330 [1];
FF FoxA2 T02513 and FoxD3 show an additive, not synergistic, activation of the FoxA2 promoter R16331 [1];
FF dose dependent activation of the FoxA2 promoter at all tested concentrations [1];
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IN T00652 Oct3-isoform1; human, Homo sapiens.
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MX M00130 V$FOXD3_01.
MX M04241 V$FOXD3_05.
MX M00809 V$FOX_Q2.
MX M07319 V$HFH2_Q5.
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BS R72412.
BS R63497.
BS R63434.
BS R63457.
BS R69779.
BS R42073.
BS R56150.
BS R56151.
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DR TRANSPATH: MO000028060.
DR UniProtKB: Q9UJU5;
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RN [1]; RE0025441.
RX PUBMED: 11891324.
RA Guo Y., Costa R., Ramsey H., Starnes T., Vance G., Robertson K., Kelley M., Reinbold R., Scholer H., Hromas R.
RT The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression.
RL Proc. Natl. Acad. Sci. USA 99:3663-3667 (2002).
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