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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T02763 XX ID T02763 XX DT 07.06.1999 (created); mpr. DT 19.09.2014 (updated); yre. CO Copyright (C), QIAGEN. XX FA EAR2 XX SY COUP-TF3; ear-2; ERBAL2; NR2F6. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G006491 NR2F6; HGNC: NR2F6. XX CL C0002; CC (rec); 2.1.3.5.3. XX SF like EAR3, predicted to encode proteins that are very similar in primary structure to receptors for steroid hormones or thyroid hormone (T3); SF amino acid sequences of the EAR2 and EAR3 gene products are very similar each other especially at the DNA binding domain (86% homology) and at the putative ligand binding domain (76% homology) [2]; XX CP human fetus: liver [2]. XX IN T00045 COUP-TF2; human, Homo sapiens. IN T00851 T3R-beta1; human, Homo sapiens. XX MX M01728 V$EAR2_Q2. MX M08805 V$EAR2_Q4. XX BS R22497. BS R20399. XX DR TRANSPATH: MO000026737. DR UniProtKB: P10588; XX RN [1]; RE0013625. RX PUBMED: 10219237. RA Nuclear Receptors Nomenclature Committee. RT A unified nomenclature system for the nuclear receptor superfamily RL Cell 97:161-163 (1999). RN [2]; RE0013627. RX PUBMED: 2905047. RA Miyajima N., Kadowaki Y., Fukushige S., Shimizu S., Semba K., Yamanashi Y., Matsubara K., Toyoshima K., Yamamoto T. RT Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other RL Nucleic Acids Res. 16:11057-11074 (1988). RN [3]; RE0047804. RX PUBMED: 10713182. RA Zhu X. G., Park K. S., Kaneshige M., Bhat M. K., Zhu Q., Mariash C. N., McPhie P., Cheng S. Y. RT The orphan nuclear receptor Ear-2 is a negative coregulator for thyroid hormone nuclear receptor function. RL Mol. Cell. Biol. 20:2604-2618 (2000). RN [4]; RE0054989. RX PUBMED: 15604093. RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M. RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. RL Mol. Cell. Proteomics 4:205-213 (2005). XX //