AC T02763
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ID T02763
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DT 07.06.1999 (created); mpr.
DT 19.09.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA EAR2
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SY COUP-TF3; ear-2; ERBAL2; NR2F6.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G006491 NR2F6; HGNC: NR2F6.
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CL C0002; CC (rec); 2.1.3.5.3.
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SF like EAR3, predicted to encode proteins that are very similar in primary structure to receptors for steroid hormones or thyroid hormone (T3);
SF amino acid sequences of the EAR2 and EAR3 gene products are very similar each other especially at the DNA binding domain (86% homology) and at the putative ligand binding domain (76% homology) [2];
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CP human fetus: liver [2].
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IN T00045 COUP-TF2; human, Homo sapiens.
IN T00851 T3R-beta1; human, Homo sapiens.
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MX M01728 V$EAR2_Q2.
MX M08805 V$EAR2_Q4.
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BS R22497.
BS R20399.
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DR TRANSPATH: MO000026737.
DR UniProtKB: P10588;
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RN [1]; RE0013625.
RX PUBMED: 10219237.
RA Nuclear Receptors Nomenclature Committee.
RT A unified nomenclature system for the nuclear receptor superfamily
RL Cell 97:161-163 (1999).
RN [2]; RE0013627.
RX PUBMED: 2905047.
RA Miyajima N., Kadowaki Y., Fukushige S., Shimizu S., Semba K., Yamanashi Y., Matsubara K., Toyoshima K., Yamamoto T.
RT Identification of two novel members of erbA superfamily by molecular cloning: the gene products of the two are highly related to each other
RL Nucleic Acids Res. 16:11057-11074 (1988).
RN [3]; RE0047804.
RX PUBMED: 10713182.
RA Zhu X. G., Park K. S., Kaneshige M., Bhat M. K., Zhu Q., Mariash C. N., McPhie P., Cheng S. Y.
RT The orphan nuclear receptor Ear-2 is a negative coregulator for thyroid hormone nuclear receptor function.
RL Mol. Cell. Biol. 20:2604-2618 (2000).
RN [4]; RE0054989.
RX PUBMED: 15604093.
RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M.
RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
RL Mol. Cell. Proteomics 4:205-213 (2005).
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