AC T02947
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ID T02947
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DT 14.02.2000 (created); sth.
DT 18.07.2014 (updated); asv.
CO Copyright (C), QIAGEN.
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FA E2F-3A
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SY E2F transcription factor 3; E2F3; E2F3a; E2F3b; TRANSCRIPTION FACTOR E2F3.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002037 E2f3.
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CL C0023; fork head.
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SZ 356 AA; 39.0 kDa (cDNA) (calc.).
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SQ CSSPTLLEQPPAPGRGGGGGPPAKRRLELGESGHQYLSDGLKTPKGKGRAALRSPDSPKT
SQ PKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLKVQKRRIYDITNVLEGIH
SQ LIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEVTELSQEEKKLDELIQSCTLDLKLLTE
SQ DSENQRLAYVTYQDIRKISGLKDQTVILVKAPPETRLEVPDSIESLQIHLASTQGPIEVY
SQ LCPEETETHRPMKTNNQDHNGNIPKPTSKDLASNNSGHSDCSVSTANLSPLASPANLLQQ
SQ TEDQIPSNLEGPFVNLLPPLLQEDYLLSLGEEEGISDLFDAYDLEKLPLVEDFMCS
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SC translated from EMBL #AF015948 (partial cds.)
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FT 69 134 PF02319; E2F/DP family winged-helix DNA-binding domai.
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SF prior to crystal structure belongs to bHLH-zip factors [2];
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IN T00810 TFEA-xbb2; mouse, Mus musculus.
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MX M02743 V$E2F3_03.
MX M02847 V$E2F4_04.
MX M00050 V$E2F_02.
MX M00803 V$E2F_Q2.
MX M00918 V$E2F_Q3_01.
MX M00919 V$E2F_Q4_01.
MX M00939 V$E2F_Q4_02.
MX M08875 V$E2F_Q4_03.
MX M00920 V$E2F_Q6_01.
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BS R09542.
BS R09543.
BS R62943.
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DR TRANSPATH: MO000004281.
DR TRANSCOMPEL: C00427.
DR EMBL: AF015948;
DR UniProtKB: O35261;
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RN [1]; RE0014062.
RX PUBMED: 9376316.
RA Dagnino L., Fry C. J., Bartley S. M., Farnham P., Gallie B. L., Phillips R. A.
RT Expression patterns of the E2F family of transcription factors during mouse nervous system development
RL Mech. Dev. 66:13-25 (1997).
RN [2]; RE0015322.
RX PUBMED: 10090723.
RA Zheng N., Fraenkel E., Pabo C. O., Pavletich N. P.
RT Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP
RL Genes Dev. 13:666-674 (1999).
RN [3]; RE0070084.
RX PUBMED: 19917728.
RA Martinez L. A., Goluszko E., Chen H. Z., Leone G., Post S., Lozano G., Chen Z., Chauchereau A.
RT E2F3 is a mediator of DNA damage-induced apoptosis.
RL Mol. Cell. Biol. 30:524-536 (2010).
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