AC T02991
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ID T02991
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DT 24.02.2000 (created); rio.
CO Copyright (C), QIAGEN.
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FA unc-4
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SY ceh-4; unc-4.
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OS Caenorhabditis elegans
OC eukaryota; animalia; metazoa; nematoda; secernentea; rhabditia; rhabditida; rhabditina; rhabditoidea; rhabditidae
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CL C0006; homeo.
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SZ 252 AA; 28.4 kDa (cDNA) (calc.).
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SQ MIGALHACVDAEPKIINDIWADFWKSQINSVLLNPSDGSETYLASDNGKSTSSREQSTSP
SQ DDDNLLMNEDDGIALEDDNDTGESAAKRRRTRTNFSGWQLEELESAFEASHYPDVFMREA
SQ LAMRLDLLESRVQVWFQNRRAKWRKREQNRNGSSEIKKDDGEQMETKALPTFPFSIDSIL
SQ AVSRVPRGRRPNAKYPRVQACKNLSPFMIPLFPITQPGGNVIREKSPPLPTQQSQIVATN
SQ ALTTVAELLKSV
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SC translated from EMBL #Z47072
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FT 86 146 
PS50071; HOMEOBOX_2.
FT 88 144 
PS50552; PAX.
FT 88 150 
SM00389; HOX_1.
FT 89 145 
PF00046; Homeobox domain.
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SF phenotype of unc-4 (uncoordinated) mutants: when adults try to move backwards the mid-body bends into a tight curve with the dorsal side innermost [2];
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FF determines the pattern of synaptic input to ventral cord motor neurons [2] [3];
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IN T03401 unc-37; Caenorhabditis elegans.
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DR TRANSPATH: MO000026942.
DR EMBL: X64904;
DR EMBL: Z47072;
DR UniProtKB: P29506;
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RN [1]; RE0014127.
RX PUBMED: 2571091.
RA Buerglin T. R., Finney M., Coulson A., Ruvkun G.
RT Caenorhabditis elegans has scores of homoeobox-containing genes
RL Nature 341:239-243 (1989).
RN [2]; RE0014520.
RX PUBMED: 1538764.
RA White J. G., Southgate E., Thomson J. N.
RT Mutations in the Caenorhabditis elegans unc-4 gene alter the synaptic input to ventral cord motor neurons
RL Nature 355:838-841 (1992).
RN [3]; RE0014521.
RX PUBMED: 1347150.
RA Miller D. M., Shen M. M., Shamu C. E., Burglin T. R., Ruvkun G., Dubois M. L., Ghee M., Wilson L.
RT C. elegans unc-4 gene encodes a homeodomain protein that determines the pattern of synaptic input to specific motor neurons
RL Nature 355:841-845 (1992).
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