TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T03417 XX ID T03417 XX DT 05.06.2000 (created); rio. DT 25.06.2007 (updated); ask. CO Copyright (C), QIAGEN. XX FA Hex XX SY hematopoietically expressed homeobox; HEX; HHEX; Prh; PRHX. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G006201 Hhex. XX CL C0006; homeo; XX SF early marker of endothelial precursors [1]; XX CP (4.5-6 days:) anterior visceral endoderm, (7 days:) anterior primitive streak, (early somite stage:) ventral gut endoderm, thyroid primordium, hepatic diverticulum, nascent blood islands, angioblast, endocardium, visceral yolk sac, allantois [1]. XX FF Hex protein activates its own promoter activity [3]; FF probably role in anteroposterior patterning, anterior gut patterning, vasculogenesis, angiogenesis and cardiac induction [1]; XX IN T08441 Sox-10; rat, Rattus norvegicus. XX DR TRANSPATH: MO000027353. DR UniProtKB: P43120; XX RN [1]; RE0014567. RX PUBMED: 9389666. RA Thomas P. Q., Brown A., Beddington R. S. RT Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors RL Development 125:85-94 (1998). RN [2]; RE0048308. RX PUBMED: 16582099. RA Wissmuller S., Kosian T., Wolf M., Finzsch M., Wegner M. RT The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. RL Nucleic Acids Res. 34:1735-1744 (2006). RN [3]; RE0050155. RX PUBMED: 15062550. RA Puppin C., Presta I., D'Elia A. V., Tell G., Arturi F., Russo D., Filetti S., Damante G. RT Functional interaction among thyroid-specific transcription factors: Pax8 regulates the activity of Hex promoter. RL Mol. Cell. Endocrinol. 214:117-125 (2004). XX //