AC T03417
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ID T03417
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DT 05.06.2000 (created); rio.
DT 25.06.2007 (updated); ask.
CO Copyright (C), QIAGEN.
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FA Hex
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SY hematopoietically expressed homeobox; HEX; HHEX; Prh; PRHX.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006201 Hhex.
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CL C0006; homeo; 3.1.2.8.1.
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SF early marker of endothelial precursors [1];
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CP (4.5-6 days:) anterior visceral endoderm, (7 days:) anterior primitive streak, (early somite stage:) ventral gut endoderm, thyroid primordium, hepatic diverticulum, nascent blood islands, angioblast, endocardium, visceral yolk sac, allantois [1].
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FF Hex protein activates its own promoter activity [3];
FF probably role in anteroposterior patterning, anterior gut patterning, vasculogenesis, angiogenesis and cardiac induction [1];
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IN T08441 Sox-10; rat, Rattus norvegicus.
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DR TRANSPATH: MO000027353.
DR UniProtKB: P43120;
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RN [1]; RE0014567.
RX PUBMED: 9389666.
RA Thomas P. Q., Brown A., Beddington R. S.
RT Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors
RL Development 125:85-94 (1998).
RN [2]; RE0048308.
RX PUBMED: 16582099.
RA Wissmuller S., Kosian T., Wolf M., Finzsch M., Wegner M.
RT The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
RL Nucleic Acids Res. 34:1735-1744 (2006).
RN [3]; RE0050155.
RX PUBMED: 15062550.
RA Puppin C., Presta I., D'Elia A. V., Tell G., Arturi F., Russo D., Filetti S., Damante G.
RT Functional interaction among thyroid-specific transcription factors: Pax8 regulates the activity of Hex promoter.
RL Mol. Cell. Endocrinol. 214:117-125 (2004).
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