AC T08441
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ID T08441
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DT 19.01.2006 (created); elf.
DT 11.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Sox-10
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SY sox10; SRY-box containing gene 10; Transcription factor SOX-10.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G021595 Sox10.
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CL C0015; HMG.
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SZ 466 AA; 50.0 kDa (cDNA) (calc.).
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SQ MAEEQDLSEVELSPVGSEEPRCLSPSSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQD
SQ GEADDDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARR
SQ KLADQYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKN
SQ GKAAQGEAECPGGETDQGGAAAIQAHYKSAHLDHRHPEEGSPMSDGNPEHPSGQSHGPPT
SQ PPTTPKTELQSGKADPKRDGRSLGEGGKPHIDFGNVDIGEISHEVMSNMETFDVTELDQY
SQ LPPNGHPGHVGSYSAAGYGLSSALAVASGHSAWISKPPGVALPTVSPPAVDAKAQVKTET
SQ TGPQGPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHAGQASG
SQ LYSAFSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
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SC translated from EMBL:AJ001029
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FT 78 452 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 103 173 
SM00398; hmgende2.
FT 104 172 
PF00505; HMG (high mobility group) box.
FT 104 172 
PS50118; HMG_BOX_2.
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CP expression in Schwann cells [1].
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FF activation of protein zero gene (P0) gene expression by induction of Sox-10 [1];
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IN T02967 Alx-4; mouse, Mus musculus.
IN T00658 BRN1; mouse, Mus musculus.
IN T09357 BRN1; mouse, Mus musculus.
IN T08466 c-Jun; rat, Rattus norvegicus.
IN T00108 C/EBPalpha-isoform1; rat, Rattus norvegicus.
IN T03989 Dlx-5; mouse, Mus musculus.
IN T18895 Egr-2-isoform1; rat, Rattus norvegicus.
IN T03417 Hex; mouse, Mus musculus.
IN T09354 Hex; mouse, Mus musculus.
IN T00378 HOXA3; mouse, Mus musculus.
IN T01790 HTF4alpha; rat, Rattus norvegicus.
IN T10173 M-Twist; mouse, Mus musculus.
IN T04047 Mox1; mouse, Mus musculus.
IN T09363 Oct3; mouse, Mus musculus.
IN T09290 OLIG2; mouse, Mus musculus.
IN T09162 Pax-3; mouse, Mus musculus.
IN T16574 Pax-3; rat, Rattus norvegicus.
IN T00681 Pax-6; mouse, Mus musculus.
IN T00007 PRDII-BF1; mouse, Mus musculus.
IN T08484 Sp1-isoform1; human, Homo sapiens.
IN T08886 UTF1-isoform1; mouse, Mus musculus.
IN T09523 UTF1; mouse, Mus musculus.
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MX M07338 V$SOX10_Q3.
MX M01131 V$SOX10_Q6.
MX M02116 V$SOX10_Q6_01.
MX M08899 V$SOX_Q4.
MX M01014 V$SOX_Q6.
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BS R29636.
BS R35722.
BS R35723.
BS R35724.
BS R35725.
BS R35726.
BS R35727.
BS R29691.
BS R18733.
BS R18738.
BS R18739.
BS R18740.
BS R18742.
BS R18743.
BS R18744.
BS R18745.
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DR TRANSPATH: MO000057857.
DR EMBL: AJ001029; RNSOX10.
DR UniProtKB: O55170; SOX10_RAT.
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RN [1]; RE0024386.
RX PUBMED: 10757804.
RA Peirano R. I., Goerich D. E., Riethmacher D., Wegner M.
RT Protein zero gene expression is regulated by the glial transcription factor Sox10.
RL Mol. Cell. Biol. 20:3198-3209 (2000).
RN [2]; RE0024470.
RX PUBMED: 12668617.
RA Lang D., Epstein J. A.
RT Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer.
RL Hum. Mol. Genet. 12:937-945 (2003).
RN [3]; RE0048308.
RX PUBMED: 16582099.
RA Wissmuller S., Kosian T., Wolf M., Finzsch M., Wegner M.
RT The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
RL Nucleic Acids Res. 34:1735-1744 (2006).
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