AC T08886
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ID T08886
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DT 03.05.2006 (created); sla.
DT 30.10.2006 (updated); jay.
CO Copyright (C), QIAGEN.
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FA UTF1-isoform1
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SY undifferentiated embryonic cell transcription factor 1; UTF1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009638 Utf1.
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CL C0009; ZIP.
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SZ 339 AA; 36.4 kDa (cDNA) (calc.).
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SQ MLLRPRRLPAFSPPSPASPDAELRSAGDVPVTTSDAFATSGGMAEPGSPKAPVSPDSAQR
SQ TPWSARETELLLGTLLQPAMWRSLLLDRRQTLPTYRRVSAALARQQVRRTPAQCRRRYKF
SQ LKDKLRDSQGQPSGPFDNQIRQLMGLLGDDGPPRVRRRSTGPGRPQRRGRSSLSALAPAP
SQ APVEQEAELPLAAENDEPAPALRFSSSTTKSAGAHRITSSPPLTSTDTLPPEPGHTFESS
SQ PTPTPDHDVETPNEPPGLSQGRASSPQVAPQSLNTALLQTLTHLGDISTVLGPLRDQLST
SQ LNQHVEHLRGSFDQTVSLAVGFILGSAASERGILGDLRQ
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SC translated from EMBL:D31647
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CP undifferentiated EC cells (F9 and P19), embryonic stem cells (ES), low level in ovary and testis of 8 week old mice, inner cell mass of blastocyst (3.5 dpc), primitive ectoderm at 6.5-7.5 dpc, low level in the neural fold at 8 dpc, strong level in the chorion at 8 dpc and furthermore detected until 13.5 dpc [2].
CN liver, kidney, spleen, lung, and brain of 8 week old mice, morula at 3dpc, trophectoderm at 3.5 dpc, mesoderm at 6.5-7.5 dpc, [2].
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FF boost adenovirus E2A promoter activity via direct interaction with the activation domain of the promoter-bound ATF-2 protein [2];
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IN T08441 Sox-10; rat, Rattus norvegicus.
IN T14088 Sox-8; mouse, Mus musculus.
IN T09097 SRY; human, Homo sapiens.
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DR TRANSPATH: MO000080911.
DR EMBL: D31647; D31647.
DR UniProtKB: Q6J1H4; O70530.
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RN [1]; RE0048308.
RX PUBMED: 16582099.
RA Wissmuller S., Kosian T., Wolf M., Finzsch M., Wegner M.
RT The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors.
RL Nucleic Acids Res. 34:1735-1744 (2006).
RN [2]; RE0047690.
RX PUBMED: 9524124.
RA Okuda A., Fukushima A., Nishimoto M., Orimo A., Yamagishi T., Nabeshima Y., Kuro-o M., Nabeshima Y., Boon K., Keaveney M., Stunnenberg H. G., Muramatsu M.
RT UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells.
RL EMBO J. 17:2019-2032 (1998).
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