TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T03503 XX ID T03503 XX DT 28.06.2000 (created); rio. DT 28.04.2010 (updated); jig. CO Copyright (C), QIAGEN. XX FA rax XX SY retinal homeobox protein 1; Rx; RX1A. XX OS clawed frog, Xenopus laevis OC eukaryota; animalia; metazoa; chordata; vertebrata; amphibia; lissamphibia; anura; archeobatrachia; pipoidea; pipidae XX GE G092367 rax.S. XX HO Rax (mouse) T03502. XX CL C0006; homeo; 3.1.3.22.1. XX SF embryos with overexpressed rax develop ectopic retinal epithelium and display hyperproliferation in the neuroretina [1]; SF rax represents one of the most anteriorly expressed homeobox genes [2]; SF extended dorsalizing signals elicited by LiCl treatment are able to induce ectopic expression of rax [2]; XX CP (early neurula stage 12.5-17:) anterior neural plate, neural ridge, putative forebrain, optic vesicles, (stage 18-27:) optic cups, retina primordia, pineal gland, ventral forebrain (stage 40:) inner neuroblastic layer [2] [1]. CN developing lens [1]. XX FF probably important role of the Rx family in the establishment and/or proliferation of retinal progenitor cells [1]; FF may have a role in the genetic control of circadian rhythms [2]; XX MX M00623 V$CRX_Q4. MX M01389 V$RAX_01. XX DR TRANSPATH: MO000027438. DR UniProtKB: O42201; XX RN [1]; RE0006132. RX PUBMED: 9177348. RA Mathers P.H., Ginsberg A., Mahon K. A., Jamrich M. RT The Rx homeobox gene is essential for vertebrate eye development RL Nature 387:603-607 (1997). RN [2]; RE0014720. RX PUBMED: 9076688. RA Casarosa S., Andreazzoli M., Simeone A., Barsacchi G. RT Xrx1, a novel Xenopus homeobox gene expressed during eye and pineal gland development RL Mech. Dev. 61:187-198 (1997). XX //