AC T04281
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ID T04281
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DT 01.02.2001 (created); rio.
DT 18.07.2008 (updated); tgo.
CO Copyright (C), QIAGEN.
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FA Irx-1
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SY iroquois-related homeobox factor 1; Irx1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002733 Irx1.
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CL C0006; homeo; 3.1.4.1.1.
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SF TALE (three amino acid loop extension) homeo domain superclass [1];
SF Irx-1 and Irx-2 T04282 have similar expression patterns but Irx-2 T04282 is exclusively expressed in the follicles of wiskers [2];
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CP expression is restricted to the midbrain-hindbrain junction, expression in the developing spinal cord [3].
EX atrioventricular bundle trunk,,,Theiler Stage 26; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX epithelium of respiratory region of nasal cavity,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX foregut,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX future mesencephalon,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX future metencephalon,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX inner nuclear layer of retina,,,Theiler Stage 25; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX interventricular septum,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX interventricular septum,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX interventricular septum,,,Theiler Stage 24; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX interventricular septum,,,Theiler Stage 25; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX interventricular septum,,,Theiler Stage 26; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX lung,,,Theiler Stage 26; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX neural layer of retina,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX olfactory epithelium,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX pharyngeal arches,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX rhombencephalon,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX somite,,,Theiler Stage 17; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
EX trabeculae carneae,cardiac myocyte,,Theiler Stage 17; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [2].
EX ventricle of heart (right and left),,,Theiler Stage 17; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [3].
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FF role in specification of septum and components of the ventricular conduction system [2];
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DR TRANSPATH: MO000028145.
DR UniProtKB: P81068;
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RN [1]; RE0014544.
RX PUBMED: 9336443.
RA Burglin T. R.
RT Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals
RL Nucleic Acids Res. 25:4173-4180 (1997).
RN [2]; RE0015698.
RX PUBMED: 10926765.
RA Christoffels V. M., Keijser A. G., Houweling A. C., Clout D. E., Moorman A. F.
RT Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart
RL Dev. Biol. 224:263-274 (2000).
RN [3]; RE0035294.
RX PUBMED: 10704856.
RA Cohen D. R., Cheng C. W., Cheng S. H., Hui C. C.
RT Expression of two novel mouse Iroquois homeobox genes during neurogenesis.
RL Mech. Dev. 91:317-321 (2000).
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