AC T04283
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ID T04283
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DT 01.02.2001 (created); rio.
DT 18.07.2008 (updated); tgo.
CO Copyright (C), QIAGEN.
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FA Irx-5
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SY iroquois-related homeobox factor 5; Irx5.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004479 Irx5.
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CL C0006; homeo; 3.1.4.1.5.
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SF TALE (three amino acid loop extension) homeo domain superclass [1];
SF homeo domain is identical to human IRX2a T02436 and Irx-2 T04282 of mouse [3];
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CP (embryo 9 days:) ventricular myocardium, outer curvature, (embryo 9.5-13 days:) atrial and ventricular myocardium, trabeculated myocardium of the right ventricle [2]; expression is restricted to the midbrain-hindbrain junction, expression in the developing spinal cord [4].
EX aortic arch,,,Theiler Stage 15; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX atrio-ventricular canal,,,Theiler Stage 15; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX atrio-ventricular canal,,,Theiler Stage 19; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX atrium of heart (right and left),,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX atrium of heart (right and left),,,Theiler Stage 17; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX endocardial cushion tissue,,,Theiler Stage 15; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX endocardial cushion tissue,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX endocardial tissue of outflow tract,,,Theiler Stage 15; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX endocardial tissue of outflow tract,,,Theiler Stage 19; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX endocardium of inflow tract of heart,,,Theiler Stage 15; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX endocardium of inflow tract of heart,,,Theiler Stage 19; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX endocardium of ventriculoinfundibular fold,,,Theiler Stage 15; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX endocardium of ventriculoinfundibular fold,,,Theiler Stage 19; none; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX forelimb bud,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX forelimb bud,,,Theiler Stage 17; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX future mesencephalon,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX future metencephalon,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX inner nuclear layer of retina,,,Theiler Stage 25; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX interventricular septum,,,Theiler Stage 15; low; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX interventricular septum,,,Theiler Stage 19; low; RNA-in situ hybridization (not further specified); RNA (undefined); [3].
EX liver,,,Theiler Stage 17; high; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX marginal layer of mesencephalic tegmentum,dopaminergic neuron,,Theiler Stage 19; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX pharyngeal arches,,,Theiler Stage 17; high; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX rhombencephalon,,,Theiler Stage 15; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX spinal cord,,,Theiler Stage 15; high; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX spinal cord,,,Theiler Stage 17; high; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX spinal cord,,,Theiler Stage 19; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX spinal cord,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX ventricle of heart (right and left),,,Theiler Stage 17; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX ventricular layer of mesencephalon,dopaminergic neuron,,Theiler Stage 19; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
EX ventricular layer of the cerebral cortex,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [4].
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FF may play a role for the distinction between primary and chamber myocardium [2];
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MX M01472 V$IRX5_01.
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DR TRANSPATH: MO000028147.
DR UniProtKB: Q9JKQ4;
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RN [1]; RE0014544.
RX PUBMED: 9336443.
RA Burglin T. R.
RT Analysis of TALE superclass homeobox genes (MEIS, PBC, KNOX, Iroquois, TGIF) reveals a novel domain conserved between plants and animals
RL Nucleic Acids Res. 25:4173-4180 (1997).
RN [2]; RE0015697.
RX PUBMED: 10882515.
RA Christoffels V. M., Habets P. E., Franco D., Campione M., de Jong F., Lamers W. H., Bao Z. Z., Palmer S., Biben C., Harvey R. P., Moorman A. F.
RT Chamber formation and morphogenesis in the developing mammalian heart
RL Dev. Biol. 223:266-278 (2000).
RN [3]; RE0015698.
RX PUBMED: 10926765.
RA Christoffels V. M., Keijser A. G., Houweling A. C., Clout D. E., Moorman A. F.
RT Patterning the embryonic heart: identification of five mouse Iroquois homeobox genes in the developing heart
RL Dev. Biol. 224:263-274 (2000).
RN [4]; RE0035294.
RX PUBMED: 10704856.
RA Cohen D. R., Cheng C. W., Cheng S. H., Hui C. C.
RT Expression of two novel mouse Iroquois homeobox genes during neurogenesis.
RL Mech. Dev. 91:317-321 (2000).
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