AC T04300
XX
ID T04300
XX
DT 06.02.2001 (created); rio.
DT 19.04.2010 (updated); bjo.
CO Copyright (C), QIAGEN.
XX
FA Lmx1a
XX
SY LIM homeobox protein 1; Lmx-1.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G004548 Lmx1a.
XX
CL C0025; LIM-homeo; 3.1.5.6.1.
XX
SF 98% amino acid identity to Lmx1 T01958 of hamster [1];
SF dreher (dr) mutation results from a mutation in Lmx1a [1];
SF dr -/- embryos show a lack of the roof plate in the caudal portion of the neural tube and disruption of the dorsal neural specification in the spinal cord [1];
XX
CP (embryo 11.5 days, mutant mice:) roof plate, neural crest cells on either side of roof plate, rhombic lip, prospective cerebellar granule neurons, posterior cortex [1].
XX
FF development of the roof plate and specification of dorsal cell fates in the CNS and vertebrae [1];
XX
MX M01409 V$LMX1_01.
MX M07386 V$LMX1_Q2.
XX
DR TRANSPATH: MO000028158.
DR UniProtKB: Q9JKU8;
XX
RN [1]; RE0015721.
RX PUBMED: 10693804.
RA Millonig J. H., Millen K. J., Hatten M. E.
RT The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS
RL Nature 403:764-769 (2000).
RN [2]; RE0066561.
RX PUBMED: 15188402.
RA Hassel S., Eichner A., Yakymovych M., Hellman U., Knaus P., Souchelnytskyi S.
RT Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry.
RL Proteomics 4:1346-1358 (2004).
XX
//