AC T04339
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ID T04339
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DT 20.02.2001 (created); rio.
CO Copyright (C), QIAGEN.
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FA DREF
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SY DNA replication-related element binding factor.
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OS fruit fly, Drosophila virilis
OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae
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CL C0043; BED finger.
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SZ 743 AA; 84.3 kDa (gene) (calc.).
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SQ MDGVASSPMVVEAKYEDVSQLNFSKLYSPKMKSVYWRYFGFPSNDNDEVITKQNVVCIKC
SQ HKVLTNHGNTTNLRAHLQHRHKDLFKALCQENDIQVPPRKIRRNLNHPPLSKRNVSSRRV
SQ KLEFVNNRTHHENDEDEEMDEAAVAAAAMQAEDDAASQTMLYETMVPLTYDDADNLVEEE
SQ DRSISIEPRELKFARKRKSTAPSGTMHFTRANIKHEEGTGGMQVRSYITNLPEALADIVV
SQ RDLRNVETLYDLGISEFIRLAMGNLPSLPMPQKIDALITEQHASKFLEMGDFTRDFTAEK
SQ PYSLAFEQWMNVEQRRFLSIYHHYLSDETQCVRSVMYATIEYTDYISFDELLADFYLPNC
SQ TLAIVNYDDEEDLLQTYLKEKNIPVVLCYVSVIDKCLWHVFELEEVATSLEQVKDIIQRH
SQ SAEISSKVSELPAYNEHFPWTLYELLKFFAESISWSEDMDQLVITAKTVTEALSALVIAL
SQ DTLRGEDMPLCSMLSPITSKILIKKLGIAEQDEPLMMNIKRTIASVLQSQIIANDTLTSA
SQ ALLDPRFHRLTTIENLDSCVRMLTQKYNKTFGGSVGTDSQSGDSAEVAPTAPVNAPTVTI
SQ KTEPNVKSGGSSSSAAAATSHSAKKSSKTELLFDVAEIPNPPKRDADSTVETDLKRYRNE
SQ VIVQLDESPIEWWNKMGHIYGTLRDLATLYQGVPGVVNLNFKKVLREQIYDYNKRFMLTG
SQ SQNQIDAILFLNRSSSLKDTIYV
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SC translated from EMBL #AB019511
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FT 14 179 
CR1 domain [2].
FT 30 88 
BED finger domain [1].
FT 30 84 
SM00614; ZnF_BED.
FT 30 88 
PS50808; ZF_BED.
FT 33 82 
PF02892; BED zinc finger.
FT 344 680 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 432 573 
CR2 domain [2].
FT 624 731 
CR3 domain [2].
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SF three highly conserved regions (CR1, CR2 and CR3) between DREF T04324 of D. melanogaster and D. virilis [2];
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FF targeted expression of CR1 and CR2 domains to the eye imaginal discs inhibits cell cycle progression and reduces incorporation of 5-bromo-2'-deoxyuridine into the S-phase zone [2];
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DR TRANSPATH: MO000028197.
DR EMBL: AB019511;
DR UniProtKB: O96084;
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RN [1]; RE0015736.
RX PUBMED: 10973053.
RA Aravind L.
RT The BED finger, a novel DNA-binding domain in chromatin-boundary-element-binding proteins and transposases
RL Trends Biochem. Sci. 25:421-423 (2000).
RN [2]; RE0015776.
RX PUBMED: 9862973.
RA Takahashi Y., Hirose F., Matsukage A., Yamaguchi M.
RT Identification of three conserved regions in the DREF transcription factors from Drosophila melanogaster and Drosophila virilis
RL Nucleic Acids Res. 27:510-516 (1999).
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//