TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T04324 XX ID T04324 XX DT 14.02.2001 (created); rio. DT 10.04.2014 (updated); jtr. CO Copyright (C), QIAGEN. XX FA DREF XX SY CG5838; DNA replication-related element binding factor. XX OS fruit fly, Drosophila melanogaster OC eukaryota; animalia; metazoa; arthropoda; insecta; diptera; drosophiloidea; drosophilidae XX GE G002715 Dref. XX CL C0001; CH; XX SF in parts sequence conflict with published sequence [3]; SF maternally expressed [3]; SF three highly conserved regions (CR1, CR2 and CR3) between DREF T04339 of D. virilis and D. melanogaster [4]; XX CP unfertilized egg, (cycle 7-9:) all cell nuclei [3]. XX FF transactivating factor for the DNA polymerase alpha gene [3]; FF can overcome repression of Zen T00917 in a dose dependent manner [3]; FF activator of E2F T01547 expression [7]; FF targeted expression of CR1 and CR2 domains to the eye imaginal discs inhibits cell cycle progression and reduces incorporation of 5-bromo-2'-deoxyuridine into the S-phase zone [4]; FF involved in TBP T00797 expression [6]; FF probably involved in transcriptional regulation of the mitochondrial transcription factor A (mtTFA T04783) [5]; XX MX M00488 I$DREF_Q3. XX BS R60180. BS R17325. BS R17326. BS R17327. BS R60168. BS R61250. BS R61258. BS R61259. BS R11160. BS R26261. BS R17530. XX DR TRANSPATH: MO000028182. DR UniProtKB: Q94883; XX RN [1]; RE0008016. RX PUBMED: 8093616. RA Hirose F., Yamaguchi M., Handa H., Inomata Y., Matsukage A. RT Novel 8-base pair sequence (Drosophila DNA replication-related element) and specific binding factor involved in the expression of Drosophila genes for DNA polymerase alpha and proliferating cell nuclear antigen RL J. Biol. Chem. 268:2092-2099 (1993). RN [2]; RE0015736. RX PUBMED: 10973053. RA Aravind L. RT The BED finger, a novel DNA-binding domain in chromatin-boundary-element-binding proteins and transposases RL Trends Biochem. Sci. 25:421-423 (2000). RN [3]; RE0015757. RX PUBMED: 8632015. RA Hirose F., Yamaguchi M., Kuroda K., Omori A., Hachiya T., Ikeda M., Nishimoto Y., Matsukage A. RT Isolation and characterization of cDNA for DREF, a promoter-activating factor for Drosophila DNA replication-related genes RL J. Biol. Chem. 271:3930-3937 (1996). RN [4]; RE0015776. RX PUBMED: 9862973. RA Takahashi Y., Hirose F., Matsukage A., Yamaguchi M. RT Identification of three conserved regions in the DREF transcription factors from Drosophila melanogaster and Drosophila virilis RL Nucleic Acids Res. 27:510-516 (1999). RN [5]; RE0016895. RX PUBMED: 11554753. RA Takata K.-I., Yoshida H., Hirose F., Yamaguchi M., Kai M., Oshige M., Sakimoto I., Koiwai O., Sakaguchi K. RT Drosophila Mitochondrial Transcription Factor A: Characterization of Its cDNA and Expression Pattern during Development. RL Biochem. Biophys. Res. Commun. 287:474-483 (2001). RN [6]; RE0016901. RX PUBMED: 11033359. RA Choi T., Cho N., Oh Y., Yoo M., Matsukage A., Ryu Y., Han K., Yoon J., Baek K. RT The DNA replication-related element (DRE)-DRE-binding factor (DREF) system may be involved in the expression of the Drosophila melanogaster TBP gene RL FEBS Lett. 483:71-77 (2000). RN [7]; RE0016902. RX PUBMED: 9748283. RA Sawado T., Hirose F., Takahashi Y., Sasaki T., Shinomiya T., Sakaguchi K., Matsukage A., Yamaguchi M. RT The DNA replication-related element (DRE)/DRE-binding factor system is a transcriptional regulator of the Drosophila E2F gene RL J. Biol. Chem. 273:26042-26051 (1998). XX //