AC T04348
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ID T04348
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DT 22.02.2001 (created); rio.
CO Copyright (C), QIAGEN.
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FA Tbx5
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SY T-box protein 5.
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OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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CL C0044; T-box.
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SZ 521 AA; 58.4 kDa (cDNA) (calc.).
XX
SQ MADTEEGFGLPSTPVDSEAKELQAEAKQDPQLGTTSKAPTSPQAAFTQQGMEGIKVFLHE
SQ RELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNK
SQ WSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ
SQ PRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSD
SQ DMELHRMSRMQSKEYPVVPRSTVRQKVSSNHSPFSGETRVLSTSSNLGSQYQCENGVSST
SQ SQDLLPPTNPYPISQEHSQIYHCTKRKDEECSTTEHPYKKPYMETSPAEEDPFYRSSYPQ
SQ QQGLNTSYRTESAQRQACMYASSAPPTDPVPSLEDISCNTWPSVPSYSSCTVSAMQPMDR
SQ LPYQHFSAHFTSGPLMPRLSSVANHTSPQIGDTHSMFQHQTSVSHQPIVRQCGPQTGIQS
SQ PPSSLQPAEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSENS
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SC translated from EMBL #AF069396
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FT 53 243 
SM00425; tbox5.
FT 55 239 
PF00907; T-box.
FT 58 238 
PS50252; TBOX_3.
FT 63 246 
T domain [1].
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SF 88% identity to murine Tbx5 T04347 [1];
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CP (stage 8-9:) posterior-anterior gradient in cardiac primordia, (stage 16:) heart tube, (stage 20-27:) atria, left ventricle (stage 27-28:) left side of intraventricular septum, atrial myocardium, atrial septa [1].
CN (stage 20-27:) right ventricle, outflow track [1].
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FF involved in heart development especially cardiac septation and left chamber specification [1];
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MX M01044 V$TBX5_Q5.
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DR TRANSPATH: MO000028206.
DR EMBL: AF069396;
DR UniProtKB: Q9PWE8;
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RN [1]; RE0015791.
RX PUBMED: 10373308.
RA Bruneau B. G., Logan M., Davis N., Levi T., Tabin C. J., Seidman J. G., Seidman C. E.
RT Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome
RL Dev. Biol. 211:100-108 (1999).
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