TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T04359 XX ID T04359 XX DT 26.02.2001 (created); rio. DT 12.12.2014 (updated); asv. CO Copyright (C), QIAGEN. XX FA Tbx3 XX SY T-box protein 3. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G006791 Tbx3. XX CL C0044; T-box; XX SF complementary expression pattern of Tbx3 and Tbx2 T04358 in the limbs: Tbx3 is expressed throughout the distal apical ectodermal ridge (AER) whereas Tbx2 T04358 is expressed in the mesenchyme immediately underlying the posterior half of the AER [1]; XX CP (E9.5:) posterior forelimb bud margin, (E10.5-11.5:) fore-/hindlimb bud mesenchyme, apical ectodermal ridge (AER), (E12.5-13.5:) mesenchyme surrounding digit I and V, AER [1]; NIH mouse fibroblasts [2]. XX FF involved in limb morphogenesis [1]; FF may be involved in zone of polarizing (ZPA) induction [1]; XX MX M08900 V$TBX2RELATED_Q6. MX M05348 V$TBX3_02. XX BS R65250. BS R24607. BS R60160. XX DR TRANSPATH: MO000028217. DR UniProtKB: P70324; XX RN [1]; RE0015803. RX PUBMED: 8798150. RA Gibson-Brown J. J., Agulnik S. I., Chapman D. L., Alexiou M., Garvey N., Silver L. M., Papaioannou V. E. RT Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity RL Mech. Dev. 56:93-101 (1996). RN [2]; RE0053229. RX PUBMED: 15289316. RA Fan W., Huang X., Chen C., Gray J., Huang T. RT TBX3 and its isoform TBX3+2a are functionally distinctive in inhibition of senescence and are overexpressed in a subset of breast cancer cell lines. RL Cancer Res. 64:5132-5139 (2004). XX //