AC T04373
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ID T04373
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DT 08.03.2001 (created); rio.
DT 01.06.2012 (updated); uat.
CO Copyright (C), QIAGEN.
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FA EHAND
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SY heart- and neural crest derivatives-expressed 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005416 HAND1; HGNC: HAND1.
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CL C0010; bHLH; 1.2.3.2.3.
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SF 92% amino acid identity to murine Hand1 T01569 [1];
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CP (cell lines:) Jeg-3, BoWo [1].
CN (cell lines:) ED27, villous cytotrophoblasts [1].
EX brain,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX embryo,,,Carnegie Stage 23; none; Northern blot; mRNA (poly-A); [1].
EX embryo,,,Carnegie Stage 23; none; RNAse protection assay; mRNA (poly-A); [1].
EX heart,,,adult; very high; Northern blot; mRNA (poly-A); [1].
EX kidney (right and left),,,adult; none; Northern blot; mRNA (poly-A); [1].
EX liver,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX lung (right and left),,,adult; none; Northern blot; mRNA (poly-A); [1].
EX muscles,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX pancreas,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX placenta,,,adult; low; Northern blot; mRNA (poly-A); [1].
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FF may be required for early trophoblast development and persistent expression of cardiac-specific genes [1];
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MX M01034 V$EBOX_Q6_01.
MX M00222 V$HAND1E47_01.
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DR TRANSPATH: MO000028230.
DR UniProtKB: O96004;
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RN [1]; RE0015875.
RX PUBMED: 9931445.
RA Knofler M., Meinhardt G., Vasicek R., Husslein P., Egarter C.
RT Molecular cloning of the human Hand1 gene/cDNA and its tissue-restricted expression in cytotrophoblastic cells and heart.
RL Gene 224:77-86 (1998).
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