TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T04442 AS T22449. XX ID T04442 XX DT 20.04.2001 (created); dkl. DT 28.11.2012 (updated); ili. CO Copyright (C), QIAGEN. XX FA Smad2-short XX SY SMAD-2 (437 AA). XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002225 SMAD2; HGNC: SMAD2. XX CL C0041; SMAD; 7.1.1.1.2.2. XX SZ 437 AA; 48.9 kDa (cDNA) (calc.). XX SQ MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE SQ LEKAITTQNCNTKCVTIPSSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE SQ YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI SQ EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE SQ PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR SQ HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF SQ AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD SQ KVLTQMGSPSVRCSSMS XX SC translated from EMBL #HSU65109 XX FT 10 146 PS51075; MH1. FT 36 144 SM00523; dwAneu5. FT 38 141 PF03165; MH1 domain. FT 238 415 PF03166; MH2 domain. FT 242 413 SM00524; DWB. FT 244 437 PS51076; MH2. XX SF splice variant of Smad2, human T04095, lacking exon 3, making up 1/10 of Smad2 transcripts in certain tissues and cells, e.g. HaCaT human keratinocyte cells, placenta cells, Molt-4 human T cell leukemia cell line, HEL human erythroleukemia cell line and U937 human monocyte leukemia cell line [1] [2]; SF amino acid sequence was translated from EMBL #HSU65109 and modified by removing amino acids from position 80 to 109, exon 3 in SMAD-2 [1] [2]; XX MX M08897 V$SMAD_Q4. MX M00792 V$SMAD_Q6. MX M00974 V$SMAD_Q6_01. XX DR TRANSPATH: MO000028292. DR EMBL: U65019; DR UniProtKB: Q15796-2; XX RN [1]; RE0015715. RX PUBMED: 9503010. RA Takenoshita S., Mogi A., Nagashima M., Yang K., Yagi K., Hanyu A., Nagamachi Y., Miyazono K., Hagiwara K. RT Characterization of the MADH2/Smad2 gene, a human Mad homolo responsible for the transforming growth factor-beta and activin signal transduction pathway RL Genomics 48:1-11 (1998). RN [2]; RE0016055. RX PUBMED: 9873005. RA Yagi K., Goto D., Hamamoto T., Takenoshita S., Kato M., Miyazono K. RT Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3. RL J. Biol. Chem. 274:703-709 (1999). XX //