AC T04442
AS T22449.
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ID T04442
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DT 20.04.2001 (created); dkl.
DT 28.11.2012 (updated); ili.
CO Copyright (C), QIAGEN.
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FA Smad2-short
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SY SMAD-2 (437 AA).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002225 SMAD2; HGNC: SMAD2.
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CL C0041; SMAD; 7.1.1.1.2.2.
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SZ 437 AA; 48.9 kDa (cDNA) (calc.).
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SQ MSSILPFTPPVVKRLLGWKKSAGGSGGAGGGEQNGQEEKWCEKAVKSLVKKLKKTGRLDE
SQ LEKAITTQNCNTKCVTIPSSLDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENCE
SQ YAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGI
SQ EPQSNYIPETPPPGYISEDGETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSE
SQ PAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRR
SQ HIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEF
SQ AALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLD
SQ KVLTQMGSPSVRCSSMS
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SC translated from EMBL #HSU65109
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FT 10 146 
PS51075; MH1.
FT 36 144 
SM00523; dwAneu5.
FT 38 141 
PF03165; MH1 domain.
FT 238 415 
PF03166; MH2 domain.
FT 242 413 
SM00524; DWB.
FT 244 437 
PS51076; MH2.
XX
SF splice variant of Smad2, human T04095, lacking exon 3, making up 1/10 of Smad2 transcripts in certain tissues and cells, e.g. HaCaT human keratinocyte cells, placenta cells, Molt-4 human T cell leukemia cell line, HEL human erythroleukemia cell line and U937 human monocyte leukemia cell line [1] [2];
SF amino acid sequence was translated from EMBL #HSU65109 and modified by removing amino acids from position 80 to 109, exon 3 in SMAD-2 [1] [2];
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MX M08897 V$SMAD_Q4.
MX M00792 V$SMAD_Q6.
MX M00974 V$SMAD_Q6_01.
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DR TRANSPATH: MO000028292.
DR EMBL: U65019;
DR UniProtKB: Q15796-2;
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RN [1]; RE0015715.
RX PUBMED: 9503010.
RA Takenoshita S., Mogi A., Nagashima M., Yang K., Yagi K., Hanyu A., Nagamachi Y., Miyazono K., Hagiwara K.
RT Characterization of the MADH2/Smad2 gene, a human Mad homolo responsible for the transforming growth factor-beta and activin signal transduction pathway
RL Genomics 48:1-11 (1998).
RN [2]; RE0016055.
RX PUBMED: 9873005.
RA Yagi K., Goto D., Hamamoto T., Takenoshita S., Kato M., Miyazono K.
RT Alternatively spliced variant of Smad2 lacking exon 3. Comparison with wild-type Smad2 and Smad3.
RL J. Biol. Chem. 274:703-709 (1999).
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