AC T04452
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ID T04452
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DT 30.04.2001 (created); rio.
CO Copyright (C), QIAGEN.
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FA Barx2b
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G001922 Barx2.
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HO BarH1T03926, BarH2T03927 (Drosophila).
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CL C0006; homeo.
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SZ 283 AA; 31.5 kDa (cDNA) (calc.).
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SQ MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHS
SQ CTGSPSLRAYPLLSVITRQPTVISHLVPTGSGLTPVLTRHPVAAAEAAAAAAETPGGEAL
SQ ASSESETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQ
SQ VKTWYQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQSQELLES
SQ SERQEEPCDTQEPKACLVPLEVAEPIHQPQELSEASSEPPPLS
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SC sequence taken from Ref. [1]
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FT 123 133 
SRF interaction domain [1].
FT 135 195 
PS50071; HOMEOBOX_2.
FT 137 199 
SM00389; HOX_1.
FT 138 194 
PF00046; Homeobox domain.
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SF 73% amino acid identity to chicken Barx2b T03925 [1];
SF interacts with SRF T00764 and increases the affinity of SRF for a CArG box binding site [1];
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EX aorta,,,adult; high; RNAse protection assay; RNA (undefined); [1].
EX brain,,,adult; detectable; RNAse protection assay; RNA (undefined); [1].
EX heart,,,adult; none; Northern blot; total RNA; [1].
EX heart,,,adult; none; RNAse protection assay; RNA (undefined); [1].
EX ileum,,,adult; detectable; Northern blot; total RNA; [1].
EX ileum,,,adult; high; Northern blot; mRNA (poly-A); [1].
EX ileum,,,adult; high; RNAse protection assay; RNA (undefined); [1].
EX kidney (right and left),,,adult; none; RNAse protection assay; RNA (undefined); [1].
EX liver,,,adult; none; Northern blot; total RNA; [1].
EX liver,,,adult; none; RNAse protection assay; RNA (undefined); [1].
EX lung,,,adult; high; RNAse protection assay; RNA (undefined); [1].
EX muscles,,,adult; detectable; RNAse protection assay; RNA (undefined); [1].
EX spleen,,,adult; none; RNAse protection assay; RNA (undefined); [1].
EX stomach,,,adult; high; RNAse protection assay; RNA (undefined); [1].
EX urinary bladder,,,adult; detectable; Northern blot; mRNA (poly-A); [1].
EX urinary bladder,,,adult; none; Northern blot; total RNA; [1].
EX uterus,,,adult; high; Northern blot; mRNA (poly-A); [1].
EX uterus,,,adult; high; RNAse protection assay; RNA (undefined); [1].
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FF Barx2b mRNA is expressed in high levels in several smooth muscle-containing tissue;
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IN T00764 SRF; human, Homo sapiens.
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MX M01431 V$BARX2_01.
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DR TRANSPATH: MO000028302.
DR UniProtKB: O08686;
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RN [1]; RE0016089.
RX PUBMED: 11278942.
RA Herring B. P., Kriegel A. M., Hoggatt A. M.
RT Identification of Barx2b, a serum response factor-associated homeodomain protein.
RL J. Biol. Chem. 276:14482-14489 (2001).
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