AC T04541
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ID T04541
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DT 01.06.2001 (created); rio.
DT 08.04.2009 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA ipf1
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SY insulin promoter factor 1; insulin upstream factor 1; IPF-1; IPF1; Pdx-1; Pdx1; Xlhbox8.
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OS clawed frog, Xenopus laevis
OC eukaryota; animalia; metazoa; chordata; vertebrata; amphibia; lissamphibia; anura; archeobatrachia; pipoidea; pipidae
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CL C0006; homeo.
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SZ 271 AA; 31.4 kDa (cDNA) (calc.).
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SQ MNADDQYYPQAPIYKEPCAFQRSQGQDYNPSPPACLYMGRQQQAAYSNPLVALDPGSPPD
SQ ISPYEVPPISEEPIVPHLHHHHYHHHHHHPGIPHPHHQMPFPDDNESGTLEERNRTLLPF
SQ PWMKSTKSHTWKGQWTDGSYIMEQEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVEL
SQ AVMLNLTERHIKIWFQNRRMKWKKEEDKKRGRGSDPEQDSVVSSADVLKDEPQCLGNSQK
SQ TGDLVLSSPLPTSSQPNQVPSIGSLRQAEKR
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SC translated from EMBL #X16849
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FT 1 75 
transactivation domain [2].
FT 145 205 
PS50071; HOMEOBOX_2.
FT 147 209 
SM00389; HOX_1.
FT 148 204 
PF00046; Homeobox domain.
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SF N-terminal region required for transactivation and synergistic interaction with E47 T00674 and E2-5 T00433 [2];
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CP (stage 8-9:) dorsal side of vegetal pole [1].
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FF TGF-beta signaling (Vg1) induces expression at the blastula stage [1];
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MX M01233 V$IPF1_01.
MX M01234 V$IPF1_02.
MX M01235 V$IPF1_03.
MX M01236 V$IPF1_04.
MX M01255 V$IPF1_05.
MX M01438 V$IPF1_06.
MX M00436 V$IPF1_Q4.
MX M01013 V$IPF1_Q4_01.
MX M04614 V$IPF1_Q5_01.
MX M01275 V$IPF1_Q6.
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DR TRANSPATH: MO000028379.
DR EMBL: X16849;
DR UniProtKB: P14837;
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RN [1]; RE0016278.
RX PUBMED: 8631246.
RA Henry G. L., Brivanlou I. H., Kessler D. S., Hemmati-Brivanlou A., Melton D. A.
RT TGF-beta signals and a pattern in Xenopus laevis endodermal development
RL Development 122:1007-1015 (1996).
RN [2]; RE0016279.
RX PUBMED: 9199333.
RA Peshavaria M., Henderson E., Sharma A., Wright C. V., Stein R.
RT Functional characterization of the transactivation properties of the PDX-1 homeodomain protein
RL Mol. Cell. Biol. 17:3987-3996 (1997).
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