AC T04742
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ID T04742
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DT 10.09.2001 (created); rio.
DT 21.06.2016 (updated); hna.
CO Copyright (C), QIAGEN.
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FA ATF-6
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SY activating transcription factor 6; Activating transcription factor 6 alpha; ATF6-alpha; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic-AMP-dependent transcription factor.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002673 ATF6; HGNC: ATF6.
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CL C0008; bZIP; 1.1.7.3.1.
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FF direct target of endoplasmic reticulum (ER) stress response [1];
FF strong transcriptional activator of the ER chaperone GRP78 [1];
FF IRE1 can activate ATF-6 expression, i.e. it seems to act upstream of ATF-6 in the ER stress signaling pathway [1];
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IN T08562 CREB1; human, Homo sapiens.
IN T10617 NF-YC; human, Homo sapiens.
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MX M00483 V$ATF6_01.
MX M00981 V$CREBATF_Q6.
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BS R72608.
BS R26566.
BS R40681.
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DR TRANSPATH: MO000028553.
DR UniProtKB: P18850;
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RN [1]; RE0016854.
RX PUBMED: 10856300.
RA Wang Y., Shen J., Arenzana N., Tirasophon W., Kaufman R. J., Prywes R.
RT Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.
RL J. Biol. Chem. 275:27013-27020 (2000).
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