AC T04852
XX
ID T04852
XX
DT 06.11.2001 (created); rio.
DT 06.07.2011 (updated); jtr.
CO Copyright (C), QIAGEN.
XX
FA LANA
XX
SY latency-associated nuclear antigen; ORF 73.
XX
OS KSHV, Kaposi's sarcoma-associated herpesvirus (Human herpesvirus 8)
OC Viruses; dsDNA viruses, no RNA stage; Herpesviridae; Gammaherpesvirinae; Rhadinovirus
XX
SZ 1089 AA; 126.2 kDa (calc.).
XX
SQ MAPPGMRLRSGRSTGAPLTRGSCRKRNRSPERCDLGDDLHLQPRRKHVADSVDGRECGPH
SQ TLPIPGSPTVFTSGLPAFVSSPTLPVAPIPSPAPATPLPPPALLPPVTTSSSPIPPSHPV
SQ SPGTTDTHSPSPALPPTQSPESSQRPPLSSPTGRPDSSTPMRPPPSQQTTPPHSPTTPPP
SQ EPPSKSSPDSLAPSTLRSLRKRRLSSPQGPSTLNPICQSPPVSPPRCDFANRSVYPPWAT
SQ ESPIYVGSSSDGDTPPRQPPTSPISIGSSSPSEGSWGDDTAMLVLLAEIAEEASKNEKEC
SQ SENNQAGEDNGDNEISKESQVDKDDNDNKDDEEEQETDEEDEEDDEEDDEEDDEEDDEED
SQ DEEDDEEDDEEDDEEDDEEEDEEEDEEEDEEEDEEEEEDEEDDDDEDNEDEEDDEEEDKK
SQ EDEEDGGDGNKTLSIQSSQQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQEPL
SQ QEPQQQEPQQQEPQQREPQQREPQQREPQQREPQQREPQQREPQQQEPQQREPQQQEPQQ
SQ QEPQQQEPQQQEPQQQEPQQQEPQQQEPQQQDEQQQDEQQQDEQQQDEQQQDEQQQDEQQ
SQ QDEQEQQDEQQQDEQQQQDEQEQQEEQEQQEEQEQQEEQEQEQQEEQEQELEEQEQELEE
SQ QEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQE
SQ LEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQEQELEEQ
SQ EQEQELEEVEEQEQEQEEQELEEVEEQEQEQEEQEEQELEEVEEQEEQELEEVEEQEEQE
SQ LEEVEEQEQQGVEQQEQETVEEPIILHGSSSEDEMEVDYPVVSTHEQIASSPPGDNTPDD
SQ DPQPGPSREYRYVLRTSPPHRPGVRMRRVPVTHPKKPHPRYQQPPVPYRQIDDCPAKARP
SQ QHIFYRRFLGKDGRRDPKCQWKFAVIFWGNDPYGLKKLSQAFQFGGVKAGPVSCLPHPGP
SQ DQSPITYCVYVYCQNKDTSKKVQMARLAWEASHPLAGNLQSSIVKFKKPLPLTQPGENQG
SQ PGDSPQEMT
XX
SC translated from EMBL #U93872
XX
FT 563 572 
PF00904; Involucrin repeat.
FT 651 660 
PF00904; Involucrin repeat.
FT 665 674 
PF00904; Involucrin repeat.
FT 679 688 
PF00904; Involucrin repeat.
FT 693 702 
PF00904; Involucrin repeat.
FT 697 795 
PS50083; SPEC_REPEAT.
FT 707 716 
PF00904; Involucrin repeat.
FT 721 730 
PF00904; Involucrin repeat.
FT 735 744 
PF00904; Involucrin repeat.
FT 749 758 
PF00904; Involucrin repeat.
FT 763 772 PF00904; Involucrin repeat.
FT 769 839 putative leucine zipper [1].
FT 777 786 PF00904; Involucrin repeat.
XX
SF physically interacts with ATF4 T01303 [1];
XX
FF interaction with ATF T01303 inhibits its transactivation ability [1];
XX
IN T01303 ATF-4; human, Homo sapiens.
XX
BS R35850.
XX
DR TRANSPATH: MO000028652.
DR EMBL: U93872;
DR UniProtKB: O40947;
XX
RN [1]; RE0017064.
RX PUBMED: 11038375.
RA Lim C., Sohn H., Gwack Y., Choe J.
RT Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus (human herpesvirus-8) binds ATF4/CREB2 and inhibits its transcriptional activation activity
RL J. Gen. Virol. 81:2645-2652 (2000).
XX
//