AC T05131
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ID T05131
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DT 27.05.2002 (created); mas.
DT 15.04.2013 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA GLIS2
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SY Glis 2; Glis-2; Krueppel-like Zinc Finger Protein Glis2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004145 GLIS2; HGNC: Glis2.
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CL C0001; CH; 2.3.3.1.5.
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SF contains 5 zinc finger domains [1];
SF closely related to GLI and ZIC subfamily of Krueppel-like zinc finger transcription factors [1];
SF highest amino acid similarity to GLI1 (58%) with highest identities in zinc finger 3,4, and 5 [1];
SF 93% amino acid identity between human T05131 and mouse ortholog T05132 [1];
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CP (adult): high levels in kidney and lower levels in heart, lung, placenta [1]; (cell lines:) expressed in 293, 769R, HK2, H460, DU146, RAW 264.7 cells [1] [1].
EX blood,basophil granulocyte,Circulatory System & Hematopoietic System,adult; none; Northern blot; mRNA (poly-A); [1].
EX blood,eosinophil granulocyte,Circulatory System & Hematopoietic System,adult; none; Northern blot; mRNA (poly-A); [1].
EX blood,lymphocyte,Circulatory System & Hematopoietic System,adult; none; Northern blot; mRNA (poly-A); [1].
EX blood,monocyte,Circulatory System & Hematopoietic System,adult; none; Northern blot; mRNA (poly-A); [1].
EX blood,neutrophil granulocyte,Circulatory System & Hematopoietic System,adult; none; Northern blot; mRNA (poly-A); [1].
EX brain,,,adult; low; Northern blot; mRNA (poly-A); [1].
EX colon,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX heart,,,adult; low; Northern blot; mRNA (poly-A); [1].
EX kidney (right and left),,,adult; high; Northern blot; mRNA (poly-A); [1].
EX large intestine,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX liver,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX lung (right and left),,,adult; low; Northern blot; mRNA (poly-A); [1].
EX muscles,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX placenta,,,adult; low; Northern blot; mRNA (poly-A); [1].
EX small intestine,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX spleen,,,adult; none; Northern blot; mRNA (poly-A); [1].
EX thymus,,,adult; none; Northern blot; mRNA (poly-A); [1].
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MX M03904 V$GLIS2_05.
MX M05436 V$GLIS2_06.
MX M07292 V$GLI_Q3.
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DR TRANSPATH: MO000032975.
DR UniProtKB: Q9BZE0;
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RN [1]; RE0017825.
RX PUBMED: 11738817.
RA Zhang F., Jetten A. M.
RT Genomic structure of the gene encoding the human GLI-related, Kruppel-like zinc finger protein GLIS2
RL Gene 280:49-57 (2001).
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