AC T05157
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ID T05157
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DT 01.07.2002 (created); mas.
DT 30.07.2009 (updated); jag.
CO Copyright (C), QIAGEN.
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FA rax
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SY retinal homeobox protein; rx.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004518 RAX; HGNC: RAX.
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CL C0006; homeo; 3.1.3.22.1.
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SF at least 3 isoforms seem to exist due to differential splicing [1];
SF 85% amino acid identity between human T05157 and mouse T03502 orthologs [1];
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FF activator [1];
FF 2 nucleotides in the PCE-1 DNA binding site R12735 seem to determine rax T05157 versus Crax >T02792> binding specificity: rax prefers CAattag and Crax TGattag [1];
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MX M00623 V$CRX_Q4.
MX M01389 V$RAX_01.
MX M04435 V$RAX_03.
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DR TRANSPATH: MO000032990.
DR UniProtKB: Q9Y2V3;
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RN [1]; RE0017886.
RX PUBMED: 10625658.
RA Kimura A., Singh D., Wawrousek E. F., Kikuchi M., Nakamura M., Shinohara T.
RT Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression.
RL J. Biol. Chem. 275:1152-1160 (2000).
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