AC T05307
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ID T05307
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DT 24.10.2002 (created); oke.
DT 12.04.2010 (updated); pch.
CO Copyright (C), QIAGEN.
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FA FXR-isoform2
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SY farnesoid-X-receptor splice variant beta 1; NR1H4.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002745 NR1H4; HGNC: NR1H4.
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CL C0002; CC (rec); 2.1.2.7.3.2.
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SZ 482 AA; 55.5 kDa (calc.).
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SQ MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
SQ NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
SQ KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
SQ MDMYMRRKCQECRLRKCKEMGMLAECLLTEIQCKSKRLRKNVKQHADQTVNEDSEGRDLR
SQ QVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLILTEM
SQ ATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSDLLEE
SQ RIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEKLQEP
SQ LLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLCEIWD
SQ VQ
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SC translated from EMBL #AF478445
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FT 6 356 PF00478; IMP dehydrogenase / GMP reductase domai.
FT 134 205 SM00399; c4gold.
FT 134 209 PS51030; NUCLEAR_REC_DBD_2.
FT 135 210 PF00105; Zinc finger, C4 type (two domains).
FT 299 454 SM00430; holi.
FT 302 478 PF00104; Ligand-binding domain of nuclear hormon.
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SF one of the splice variants of FXR T05309 [1];
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CP colon, duodenum, kidney, fetal small intestine [1].
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MX M07256 V$FXRRXR_Q5.
MX M01268 V$FXR_Q2.
MX M00631 V$FXR_Q3.
MX M03790 V$FXR_Q5.
MX M03795 V$LXR_Q6.
MX M00964 V$PXR_Q2.
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DR TRANSPATH: MO000033912.
DR EMBL: AF478445;
DR UniProtKB: Q96RI1-4;
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RN [1]; RE0018089.
RX PUBMED: 12062799.
RA Huber R. M., Murphy K., Miao B., Link J. R., Cunningham M. R., Rupar M. J., Gunyuzlu P. L., Haws T. F., Kassam A., Powell F., Hollis G. F., Young P. R., Mukherjee R., Burn T. C.
RT Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters.
RL Gene 290:35-43 (2002).
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//