AC T05308
XX
ID T05308
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DT 24.10.2002 (created); oke.
DT 16.04.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA FXR-isoform1
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SY farnesoid-X-receptor splice variant beta 2; NR1H4.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002745 NR1H4; HGNC: NR1H4.
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CL C0002; CC (rec); 2.1.2.7.3.1.
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SZ 486 AA; 55.9 kDa (calc.).
XX
SQ MVMQFQGLENPIQISPHCSCTPSGFFMEMMSMKPAKGVLTEQVAGPLGQNLEVEPYSQYS
SQ NVQFPQVQPQISSSSYYSNLGFYPQQPEEWYSPGIYELRRMPAETLYQGETEVAEMPVTK
SQ KPRMGASAGRIKGDELCVVCGDRASGYHYNALTCEGCKGFFRRSITKNAVYKCKNGGNCV
SQ MDMYMRRKCQECRLRKCKEMGMLAECMYTGLLTEIQCKSKRLRKNVKQHADQTVNEDSEG
SQ RDLRQVTSTTKSCREKTELTPDQQTLLHFIMDSYNKQRMPQEITNKILKEEFSAEENFLI
SQ LTEMATNHVQVLVEFTKKLPGFQTLDHEDQIALLKGSAVEAMFLRSAEIFNKKLPSGHSD
SQ LLEERIRNSGISDEYITPMFSFYKSIGELKMTQEEYALLTAIVILSPDRQYIKDREAVEK
SQ LQEPLLDVLQKLCKIHQPENPQHFACLLGRLTELRTFNHHHAEMLMSWRVNDHKFTPLLC
SQ EIWDVQ
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SC translated from EMBL #AF478446
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FT 6 360 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 134 205 
SM00399; c4gold.
FT 134 209 
PS51030; NUCLEAR_REC_DBD_2.
FT 135 210 
PF00105; Zinc finger, C4 type (two domains).
FT 303 458 
SM00430; holi.
FT 306 482 
PF00104; Ligand-binding domain of nuclear hormon.
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SF one of the splice variants of FXR T05309 [1];
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MX M07256 V$FXRRXR_Q5.
MX M01268 V$FXR_Q2.
MX M00631 V$FXR_Q3.
MX M03790 V$FXR_Q5.
MX M03795 V$LXR_Q6.
MX M00964 V$PXR_Q2.
XX
DR TRANSPATH: MO000033913.
DR EMBL: AF478446;
DR UniProtKB: Q96RI1-3;
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RN [1]; RE0018089.
RX PUBMED: 12062799.
RA Huber R. M., Murphy K., Miao B., Link J. R., Cunningham M. R., Rupar M. J., Gunyuzlu P. L., Haws T. F., Kassam A., Powell F., Hollis G. F., Young P. R., Mukherjee R., Burn T. C.
RT Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters.
RL Gene 290:35-43 (2002).
XX
//