AC T05318
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ID T05318
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DT 28.10.2002 (created); oke.
DT 02.07.2010 (updated); pch.
CO Copyright (C), QIAGEN.
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FA FXR:RXR-alpha
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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CL C0002; CC (rec).
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SF heterodimer, for individual polypeptides see rat FXR T04494 and rat RXR-alpha T04383;
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FF activator in response to bile acids [1] [2] [3];
FF regulates bile acid transport [2];
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MX M00767 V$FXRIR1_Q6.
MX M07256 V$FXRRXR_Q5.
MX M01268 V$FXR_Q2.
MX M00631 V$FXR_Q3.
MX M00964 V$PXR_Q2.
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BS R13129.
BS R10075.
BS R31849.
BS R13127.
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DR TRANSPATH: MO000033923.
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RN [1]; RE0018113.
RX PUBMED: 11533040.
RA Song C. S., Echchgadda I., Baek B.-S., Ahn S. C., Oh T., Roy A. K., Chatterjee B.
RT Dehydroepiandrosterone sulfotransferase gene induction by bile acid activated farnesoid X receptor.
RL J. Biol. Chem. 276:42549-42556 (2001).
RN [2]; RE0018116.
RX PUBMED: 11387316.
RA Ananthanarayanan M., Balasubramanian N., Makishima M., Mangelsdorf D. J., Suchy F. J.
RT Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.
RL J. Biol. Chem. 276:28857-28865 (2001).
RN [3]; RE0018127.
RX PUBMED: 10360171.
RA Wang H., Chen J., Hollister K., Sowers L. C., Forman B. M.
RT Endogenous bile acids are ligands for the nuclear receptor FXR/BAR.
RL Mol. Cell 3:543-553 (1999).
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