AC T05582
XX
ID T05582
XX
DT 30.05.2003 (created); abd.
DT 10.06.2006 (updated); vma.
CO Copyright (C), QIAGEN.
XX
FA E2F
XX
SY DcE2F; Transcription factor E2F.
XX
OS carrot, Daucus carota
OC eukaryota; viridiplantae; embryobionta; magnoliophyta; magnoliopsida; rosidae; apiales; apiaceae
XX
GE G005508 E2F.
XX
HO wheat E2F, tobacco E2F, human E2F-2.
XX
CL C0023; fork head; P3.3.3.5.1.
XX
SZ 431 AA; 47.5 kDa (calc.).
XX
SQ MKPPFVPSDDYYRFGESRGVADHEADVIIVKSTPSKRKPGNYNEVESSRLSMSPAYTNTV
SQ KSPNQTPVSGKGGRVYGRSNATKSLASVPQTPMSNAGSPSPLTPAGSCRYDSSLGLLTKK
SQ FINLIKQAEDGTLDLNNAAETLEVQKRRIYDITNVLEGIGLIEKKLKNRIHWKGIDASRP
SQ GEMEDDSNVLQAEVEKLSLEEKRLDDRIREMQEKLRDLSEDEANQKWLFVTEEDIKGLEC
SQ FMNKTLIAIKAPHGTTLEVPDPDEVVDYPQRRYRIILRSTMGPIDVYLVSQFEEKFDEMN
SQ SVQPSMSLPLASSTGSNDNPAAETAIVGHGLENGTMTQDGHGVNSDLYTSEDISGGIMKI
SQ LPSELDNDADYWLLTDPSISMTDMWKTDAGVEWDGASLLNEEFELPCISPRPQTPPSGVA
SQ DVSTVANGTQR
XX
SC translated from EMBL #AJ251586
XX
FT 109 174 PF02319; E2F/DP family winged-helix DNA-binding domai.
XX
SF the DP dimerization domain and the marked box are well conserved in plant E2fs [1];
SF lacks a cyclin-binding domain but it possess an N-terminal NLS of the SV40 large T-antigen type [1];
SF forms a heterodimers with a DP partner [1];
XX
CP 40 days old plantlets: leaves, roots, hypocotyls, apical meristems, petioles.
XX
FF transcriptional activator [1];
FF expression of the DcE2F gene is strongly induced during re-entry into cell cycle [1];
FF together with a DP partner can E2F transactivate an E2F-responsive reporter gene in both plant and mammalian cells [1];
XX
IN T01548 DP-1; human, Homo sapiens.
XX
MX M01114 P$E2F_Q2.
XX
BS R13478.
XX
DR EMBL: AJ251586;
DR UniProtKB: Q9LEL4;
XX
RN [1]; RE0022889.
RX PUBMED: 10748129.
RA Albani D., Mariconti L., Ricagno S., Pitto L., Moroni C., Helin K., Cella R.
RT DcE2F, a functional plant E2F-like transcriptional activator from Daucus carota.
RL J. Biol. Chem. 275:19258-19267 (2000).
XX
//