AC T01548
XX
ID T01548
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DT 07.08.1995 (created); ewi.
DT 22.07.2014 (updated); pos.
CO Copyright (C), QIAGEN.
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FA DP-1
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SY DP1; DRTF1-polypeptide-1; hDP-1; TFDP1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004544 TFDP1; HGNC: TFDP1.
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CL C0023; fork head; 3.3.2.2.1.
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SF DP-1 is a component of DRTF1/E2F;
SF it heterodimerizes with E2F-components;
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EX brain,,,adult; medium; Northern blot; mRNA (poly-A); [2].
EX heart,,,adult; none; Northern blot; mRNA (poly-A); [2].
EX kidney (right and left),,,adult; medium; Northern blot; mRNA (poly-A); [2].
EX liver,,,adult; low; Northern blot; mRNA (poly-A); [2].
EX lung (right and left),,,adult; low; Northern blot; mRNA (poly-A); [2].
EX muscles,,,adult; high; Northern blot; mRNA (poly-A); [2].
EX pancreas,,,adult; low; Northern blot; mRNA (poly-A); [2].
EX placenta,,,adult; medium; Northern blot; mRNA (poly-A); [2].
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FF no transcriptional activation;
FF in a heterodimeric complex with a E2F-component, it provides high-affinity DNA-binding [1];
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IN T01542 E2F-1; human, Homo sapiens.
IN T09117 E2F-1; human, Homo sapiens.
IN T01544 E2F-2; human, Homo sapiens.
IN T09123 E2F-2; human, Homo sapiens.
IN T14606 E2F-3; human, Homo sapiens.
IN T01546 E2F-4; human, Homo sapiens.
IN T09130 E2F-4; human, Homo sapiens.
IN T01607 E2F-5; human, Homo sapiens.
IN T02997 E2F-6; human, Homo sapiens.
IN T05582 E2F; carrot, Daucus carota.
IN T01486 p107; human, Homo sapiens.
IN T00671 p53; human, Homo sapiens.
XX
MX M00803 V$E2F_Q2.
MX M00918 V$E2F_Q3_01.
MX M00919 V$E2F_Q4_01.
MX M00939 V$E2F_Q4_02.
MX M00920 V$E2F_Q6_01.
XX
BS R12895.
BS R25547.
BS R29524.
XX
DR TRANSPATH: MO000013458.
DR UniProtKB: Q14186;
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RN [1]; RE0003302.
RX PUBMED: 8405995.
RA Helin K., Wu C. L., Fattaey A. R., Lees J. A., Dynlacht B. D., Ngwu C., Harlow E.
RT Heterodimerization of the transcription factors E2F1 and DP-1 leads to cooperative trans-activation
RL Genes Dev. 7:1850-1861 (1993).
RN [2]; RE0010471.
RX PUBMED: 7739537.
RA Wu C.-L., Zukerberg L. R., Ngwu C., Harlow E., Lees J. A.
RT In vivo association of E2F and DP family proteins
RL Mol. Cell. Biol. 15:2536-2546 (1995).
RN [3]; RE0048940.
RX PUBMED: 16135794.
RA Datta A., Sen J., Hagen J., Korgaonkar C. K., Caffrey M., Quelle D. E., Hughes D. E., Ackerson T. J., Costa R. H., Raychaudhuri P.
RT ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF.
RL Mol. Cell. Biol. 25:8024-8036 (2005).
XX
//