AC T09123
XX
ID T09123
XX
DT 26.07.2006 (created); jag.
DT 24.07.2014 (updated); pos.
CO Copyright (C), QIAGEN.
XX
FA E2F-2
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SY E2F transcription factor 2; E2F-2; E2f2.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G001702 E2F2; HGNC: E2f2.
XX
CL C0023; fork head.
XX
SZ 437 AA; 47.5 kDa (cDNA) (calc.).
XX
SQ MLQGPRALASAAGQTPKVVPAMSPTELWPSGLSSPQLCPATATYYTPLYPQTAPPAAAPG
SQ TCLDATPHGPEGQVVRCLPAGRLPAKRKLDLEGIGRPVVPEFPTPKGKCIRVDGLPSPKT
SQ PKSPGEKTRYDTSLGLLTKKFIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQ
SQ LIRKKAKNNIQWVGRGMFEDPTRPGKQQQLGQELKELMNTEQALDQLIQSCSLSFKHLTE
SQ DKANKRLAYVTYQDIRAVGNFKEQTVIAVKAPPQTRLEVPDRTEDNLQIYLKSTQGPIEV
SQ YLCPEEVQEPDSPSEEPLPSTSTLCPSPDSAQPSSSTDPSIMEPTASSVPAPAPTPQQAP
SQ PPPSLVPLEATDSLLELPHPLLQQTEDQFLSPTLACSSPLISFSPSLDQDDYLWGLEAGE
SQ GISDLFDSYDLGDLLIN
XX
SC translated from EMBL #L22846
XX
FT 129 194 
PF02319; E2F/DP family winged-helix DNA-binding domai.
XX
IN T01548 DP-1; human, Homo sapiens.
IN T03000 DP-2; human, Homo sapiens.
IN T00752 Sp1; mouse, Mus musculus.
XX
MX M08875 V$E2F_Q4_03.
XX
BS R25908.
XX
DR TRANSPATH: MO000083613.
DR EMBL: L22846;
DR UniProtKB: Q14209;
XX
RN [1]; RE0003289.
RX PUBMED: 8246995.
RA Ivey-Hoyle M., Conroy R., Huber H. E., Goodhart P. J., Oliff A., Heimbrook D. C.
RT Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F
RL Mol. Cell. Biol. 13:7802-7812 (1993).
RN [2]; RE0003316.
RX PUBMED: 8246996.
RA Lees J. A., Saito M., Vidal M., Valentine M., Look T., Harlow E., Dyson N., Helin K.
RT The retinoblastoma protein binds to a family of E2F transcription factors
RL Mol. Cell. Biol. 13:7813-7825 (1993).
RN [3]; RE0012787.
RX PUBMED: 8657141.
RA Karlseder J., Rotheneder H., Wintersberger E.
RT Interaction of Sp1 with the growth- and cell cycle regulated transcription factor E2F
RL Mol. Cell. Biol. 16:1659-1667 (1996).
RN [4]; RE0015322.
RX PUBMED: 10090723.
RA Zheng N., Fraenkel E., Pabo C. O., Pavletich N. P.
RT Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP
RL Genes Dev. 13:666-674 (1999).
RN [5]; RE0031299.
RX PUBMED: 12411495.
RA Schlisio S., Halperin T., Vidal M., Nevins J. R.
RT Interaction of YY1 with E2Fs, mediated by RYBP, provides a mechanism for specificity of E2F function.
RL EMBO J. 21:5775-86 (2002).
RN [6]; RE0054737.
RX PUBMED: 16512785.
RA Kherrouche Z., Blais A., Ferreira E., de Launoit Y., Monte D.
RT ASK-1 (apoptosis signal-regulating kinase 1) is a direct E2F target gene.
RL Biochem. J. 396:547-556 (2006).
XX
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