AC T01544
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ID T01544
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DT 07.08.1995 (created); ewi.
DT 28.05.2015 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA E2F-2
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SY E2F transcription factor 2; E2F-2; E2f2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G001702 E2F2; HGNC: E2f2.
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CL C0023; fork head; 3.3.2.1.2.
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SF heterodimers with E2F-1 exert enhanced DNA-binding activity;
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FF transcriptional activator, synergistically acting through multiple E2F sites;
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IN T01548 DP-1; human, Homo sapiens.
IN T03000 DP-2; human, Homo sapiens.
IN T01542 E2F-1; human, Homo sapiens.
IN T01544 E2F-2; human, Homo sapiens.
IN T00671 p53; human, Homo sapiens.
IN T00722 pRb; human, Homo sapiens.
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MX M00050 V$E2F_02.
MX M08875 V$E2F_Q4_03.
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BS R04555.
BS R41210.
BS R41213.
BS R41214.
BS R41215.
BS R31205.
BS R71982.
BS R71983.
BS R71984.
BS R71990.
BS R71977.
BS R71356.
BS R71357.
BS R67974.
BS R39260.
BS R64241.
BS R64244.
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DR TRANSPATH: MO000004278.
DR UniProtKB: Q14209;
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RN [1]; RE0003289.
RX PUBMED: 8246995.
RA Ivey-Hoyle M., Conroy R., Huber H. E., Goodhart P. J., Oliff A., Heimbrook D. C.
RT Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F
RL Mol. Cell. Biol. 13:7802-7812 (1993).
RN [2]; RE0003316.
RX PUBMED: 8246996.
RA Lees J. A., Saito M., Vidal M., Valentine M., Look T., Harlow E., Dyson N., Helin K.
RT The retinoblastoma protein binds to a family of E2F transcription factors
RL Mol. Cell. Biol. 13:7813-7825 (1993).
RN [3]; RE0015322.
RX PUBMED: 10090723.
RA Zheng N., Fraenkel E., Pabo C. O., Pavletich N. P.
RT Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP
RL Genes Dev. 13:666-674 (1999).
RN [4]; RE0049544.
RX PUBMED: 10965846.
RA Denis G. V., Vaziri C., Guo N., Faller D. V.
RT RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F.
RL Cell Growth Differ. 11:417-424 (2000).
RN [5]; RE0070084.
RX PUBMED: 19917728.
RA Martinez L. A., Goluszko E., Chen H. Z., Leone G., Post S., Lozano G., Chen Z., Chauchereau A.
RT E2F3 is a mediator of DNA damage-induced apoptosis.
RL Mol. Cell. Biol. 30:524-536 (2010).
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