TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T01544 XX ID T01544 XX DT 07.08.1995 (created); ewi. DT 28.05.2015 (updated); jtr. CO Copyright (C), QIAGEN. XX FA E2F-2 XX SY E2F transcription factor 2; E2F-2; E2f2. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G001702 E2F2; HGNC: E2f2. XX CL C0023; fork head; XX SF heterodimers with E2F-1 exert enhanced DNA-binding activity; XX FF transcriptional activator, synergistically acting through multiple E2F sites; XX IN T01548 DP-1; human, Homo sapiens. IN T03000 DP-2; human, Homo sapiens. IN T01542 E2F-1; human, Homo sapiens. IN T01544 E2F-2; human, Homo sapiens. IN T00671 p53; human, Homo sapiens. IN T00722 pRb; human, Homo sapiens. XX MX M00050 V$E2F_02. MX M08875 V$E2F_Q4_03. XX BS R04555. BS R41210. BS R41213. BS R41214. BS R41215. BS R31205. BS R71982. BS R71983. BS R71984. BS R71990. BS R71977. BS R71356. BS R71357. BS R67974. BS R39260. BS R64241. BS R64244. XX DR TRANSPATH: MO000004278. DR UniProtKB: Q14209; XX RN [1]; RE0003289. RX PUBMED: 8246995. RA Ivey-Hoyle M., Conroy R., Huber H. E., Goodhart P. J., Oliff A., Heimbrook D. C. RT Cloning and characterization of E2F-2, a novel protein with the biochemical properties of transcription factor E2F RL Mol. Cell. Biol. 13:7802-7812 (1993). RN [2]; RE0003316. RX PUBMED: 8246996. RA Lees J. A., Saito M., Vidal M., Valentine M., Look T., Harlow E., Dyson N., Helin K. RT The retinoblastoma protein binds to a family of E2F transcription factors RL Mol. Cell. Biol. 13:7813-7825 (1993). RN [3]; RE0015322. RX PUBMED: 10090723. RA Zheng N., Fraenkel E., Pabo C. O., Pavletich N. P. RT Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP RL Genes Dev. 13:666-674 (1999). RN [4]; RE0049544. RX PUBMED: 10965846. RA Denis G. V., Vaziri C., Guo N., Faller D. V. RT RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F. RL Cell Growth Differ. 11:417-424 (2000). RN [5]; RE0070084. RX PUBMED: 19917728. RA Martinez L. A., Goluszko E., Chen H. Z., Leone G., Post S., Lozano G., Chen Z., Chauchereau A. RT E2F3 is a mediator of DNA damage-induced apoptosis. RL Mol. Cell. Biol. 30:524-536 (2010). XX //