AC T05870
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ID T05870
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DT 17.02.2004 (created); abd.
DT 02.07.2008 (updated); ane.
CO Copyright (C), QIAGEN.
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FA p52
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SY lyt; NF-kappaB2; NFKB2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; p50B; p52.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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CL C0020; Rel.
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SZ 454 AA; 96.8 kDa (calc.).
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SQ MDNCYDPGLDGIPEYDDFEFSPSIVEPKDPAPETADGPYLVIVEQPKQRGFRFRYGCEGP
SQ SHGGLPGASSEKGRKTYPTVKICNYEGPAKIEVDLVTHSDPPRAHAHSLVGKQCSELGVC
SQ AVSVGPKDMTAQFNNLGVLHVTKKNMMEIMIQKLQRQRLRSKPQGLTEAERRELEQEAKE
SQ LKKVMDLSIVRLRFSAFLRASDGSFSLPLKPVISQPIHDSKSPGASNLKISRMDKTAGSV
SQ RGGDEVYLLCDKVQKDDIEVRFYEDDENGWQAFGDFSPTDVHKQYAIVFRTPPYHKMKIE
SQ RPVTVFLQLKRKRGGDVSDSKQFTYYPLVEDKEEVQRKRRKALPTFSQPFGGGSHMGGGS
SQ GGSAGGYGGAGGGGSLGFFSSSLAYNPYQSGAAPMGCYPGGGGGAQMAGSRRDTDAGEGA
SQ EEPRTPPEAPQGEPQALDTLQRAREYNARLFGLA
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SC translated from EMBL #BC027423 and edited
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SF identified as a nuclear activity [1];
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FF repressor of renin gene [1];
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IN T01318 CBP; mouse, Mus musculus.
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BS R14616.
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DR TRANSPATH: MO000041068.
DR EMBL: BC027423;
DR UniProtKB: Q9WTK5;
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RN [1]; RE0023900.
RX PUBMED: 14563845.
RA Todorov V. T., Volkl S., Muller M., Bohla A., Klar J., Kunz-Schughart L. A., Hehlgans T., Kurtz A.
RT Tumor necrosis factor-alpha activates NFkappaB to inhibit renin transcription by targeting cAMP-responsive element.
RL J. Biol. Chem. 279:1458-1467 (2004).
RN [2]; RE0049976.
RX PUBMED: 17434128.
RA Huang W. C., Ju T. K., Hung M. C., Chen C. C.
RT Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB.
RL Mol. Cell 26:75-87 (2007).
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