AC T05966
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ID T05966
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DT 14.05.2004 (created); oke.
DT 15.07.2013 (updated); msr.
CO Copyright (C), QIAGEN.
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FA Elk-1
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SY Elk1; ELK1, member of ETS oncogene family.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009491 Elk1.
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CL C0016; ETS; 3.5.2.2.1.
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SF identified as a nuclear activity;
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FF regulator of muscle-specific promoters;
FF interacts with SRF T00766 and can displace myocardin from its binding site on SRF [1];
FF PDGF induces phosphorylation of Elk-1 and increases its association with SRF on the promoters of smooth muscle genes [1];
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IN T00766 SRF; rat, Rattus norvegicus.
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MX M00007 V$ELK1_01.
MX M00025 V$ELK1_02.
MX M01163 V$ELK1_03.
MX M01165 V$ELK1_04.
MX M07252 V$ELK1_Q4.
MX M03819 V$ELK1_Q6.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
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BS R00462.
BS R23149.
BS R23216.
BS R57021.
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DR TRANSPATH: MO000041967.
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RN [1]; RE0024249.
RX PUBMED: 15014501.
RA Wang Z., Wang D. Z., Hockemeyer D., McAnally J., Nordheim A., Olson E. N.
RT Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.
RL Nature 428:185-189 (2004).
RN [2]; RE0048801.
RX PUBMED: 15210726.
RA Salinas S., Briancon-Marjollet A., Bossis G., Lopez M. A., Piechaczyk M., Jariel-Encontre I., Debant A., Hipskind R. A.
RT SUMOylation regulates nucleo-cytoplasmic shuttling of Elk-1.
RL J. Cell Biol. 165:767-773 (2004).
RN [3]; RE0050580.
RX PUBMED: 15282285.
RA Tong L., Balazs R., Thornton P. L., Cotman C. W.
RT Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons.
RL J. Neurosci. 24:6799-6809 (2004).
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