AC T06431
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ID T06431
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DT 02.02.2005 (created); elf.
DT 19.11.2007 (updated); bch.
CO Copyright (C), QIAGEN.
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FA AP-2delta
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SY Tcfap2d; Tfap2d; transcription factor AP-2, delta; Transcription factor AP-2delta.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G013862 Tfap2d.
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CL C0032; bHSH; 1.3.1.0.4.
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SF exists as monomer and dimer [2];
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CP neural crest, abundant in 18,5 dpc embryo, weak in newborn mice [2].
EX Hypothalamus primordium,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX central nervous system,,,P0 (immediately after birth, postnatal development); detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX central nervous system,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX cerebellum,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX cerebral cortex,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX cerebral cortex,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX corpus striatum,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX cranial sensory ganglion,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX cranial sensory ganglion,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX ear,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX ear,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX epithelium of olfactory region of nasal cavity,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX epithelium of olfactory region of nasal cavity,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX future corpus striatum,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX hypothalamus,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX mesencephalon,,,P0 (immediately after birth, postnatal development); detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX mesencephalon,,,Theiler Stage 21; detectable; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX retina,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX retina,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX rhombencephalon,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX rhombencephalon,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX spinal cord,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX spinal cord,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX subventricular zone of the MGE (medial ganglionic eminence),,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX subventricular zone of the MGE (medial ganglionic eminence),,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX thalamus,,,P0 (immediately after birth, postnatal development); none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
EX thalamus,,,Theiler Stage 21; none; RNA-in situ hybridization (non-radioactive); RNA (undefined); [1].
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FF transactivates gene expression in eukaryotic cells [2];
FF Ap-2delta exhibited greater DNA sequence preference than did Ap-2alpha T00033 under in vitro conditions [2];
FF does probably have a role in cancer biology [2];
FF weak binding to site R16374, strong binding to site R16375 [2];
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MX M08867 V$AP2_Q4.
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DR TRANSPATH: MO000045579.
DR UniProtKB: Q91ZK0;
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RN [1]; RE0025447.
RX PUBMED: 15618518.
RA Gray P. A., Fu H., Luo P., Zhao Q., Yu J., Ferrari A., Tenzen T., Yuk D. I., Tsung E. F., Cai Z., Alberta J. A., Cheng L. P., Liu Y., Stenman J. M., Valerius M. T., Billings N., Kim H. A., Greenberg M. E., McMahon A. P., Rowitch D. H., Stiles C. D., Ma Q.
RT Mouse brain organization revealed through direct genome-scale TF expression analysis.
RL Science 306:2255-2257 (2004).
RN [2]; RE0025452.
RX PUBMED: 11522791.
RA Zhao F., Satoda M., Licht J. D., Hayashizaki Y., Gelb B. D.
RT Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties.
RL J. Biol. Chem. 276:40755-40760 (2001).
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