AC T06444
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ID T06444
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DT 10.02.2005 (created); mkl.
DT 28.03.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA BRCA2
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SY BRCA2; breast cancer 2, early onset; Breast cancer type 2 susceptibility protein; FAD; FAD1; FANCB; FANCD1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G013814 BRCA2; HGNC: BRCA2.
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IN T22386 FANCD2; human, Homo sapiens.
IN T34295 Rad51-isoform1; human, Homo sapiens.
IN T34266 Rad51; human, Homo sapiens.
IN T04683 STAT5A; human, Homo sapiens.
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DR TRANSPATH: MO000045487.
DR UniProtKB: P51587; BRCA2_HUMAN.
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RN [1]; RE0049002.
RX PUBMED: 16793542.
RA Xia B., Sheng Q., Nakanishi K., Ohashi A., Wu J., Christ N., Liu X., Jasin M., Couch F. J., Livingston D. M.
RT Control of BRCA2 cellular and clinical functions by a nuclear partner, PALB2.
RL Mol. Cell 22:719-729 (2006).
RN [2]; RE0050588.
RX PUBMED: 14636569.
RA Dong Y., Hakimi M. A., Chen X., Kumaraswamy E., Cooch N. S., Godwin A. K., Shiekhattar R.
RT Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
RL Mol. Cell 12:1087-1099 (2003).
RN [3]; RE0050647.
RX PUBMED: 16391231.
RA Greenberg R. A., Sobhian B., Pathania S., Cantor S. B., Nakatani Y., Livingston D. M.
RT Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes.
RL Genes Dev. 20:34-46 (2006).
RN [4]; RE0050745.
RX PUBMED: 17664283.
RA Kumaraswamy E., Shiekhattar R.
RT Activation of BRCA1/BRCA2-associated helicase BACH1 is required for timely progression through S Phase.
RL Mol. Cell. Biol. 27:6733-6741 (2007).
RN [5]; RE0067347.
RX PUBMED: 16239144.
RA Baillat D., Hakimi M. A., Naar A. M., Shilatifard A., Cooch N., Shiekhattar R.
RT Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
RL Cell 123:265-276 (2005).
RN [6]; RE0068584.
RX PUBMED: 19584259.
RA Zhang F., Fan Q., Ren K., Andreassen P. R.
RT PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2.
RL Mol. Cancer Res. 7:1110-1118 (2009).
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