AC T06574
AS T26856.
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ID T06574
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DT 11.07.2005 (created); ili.
DT 25.09.2013 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA MAZ-isoform2
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SY MAZ; MAZI; Myc-associated zinc finger protein; MYC-associated zinc finger protein (purine-binding transcription factor); Pur-1; Purine-binding transcription factor; SAF-2; Serum amyloid A-activating factor-1; Transcription factor Zif87; ZF87; Zinc finger protein 801; ZNF801.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002730 MAZ; HGNC: MAZ.
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CL C0001; CH.
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SZ 493 AA; 51.1 kDa (cDNA) (calc.).
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SQ MFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQ
SQ SPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAAS
SQ TVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPVASAL
SQ EKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQ
SQ LSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLS
SQ HSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVH
SQ STERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCGKMLSSAYISDHMKVHSQGPHHV
SQ CELCNKGFTTAAYLRIHAVKDHGLQAPRADRILCKLCSVHCKTPAQLAGHMQTHLGGAAP
SQ PVPGDAPQPQPTC
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SC Swiss-Prot#P56270-2
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FT 59 421 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 73 73 
MAPK phosphorylation site [1].
FT 91 112 
poly-alanine tract (19/23) [1].
FT 130 139 
poly-proline tract (9/19) [1].
FT 144 163 
poly-alanine tract (113/20) [1].
FT 190 212 
PF00096; zf-C2H2.
FT 190 212 
SM00355; c2h2final6.
FT 190 217 
PS50157; ZINC_FINGER_C2H2_2.
FT 192 212 
zinc finger 1 [1].
FT 279 301 
PF00096; zf-C2H2.
FT 279 301 SM00355; c2h2final6.
FT 279 306 PS50157; ZINC_FINGER_C2H2_2.
FT 281 301 zinc finger 2 [1].
FT 307 329 PF00096; zf-C2H2.
FT 307 329 SM00355; c2h2final6.
FT 307 334 PS50157; ZINC_FINGER_C2H2_2.
FT 309 329 zinc finger 3 [1].
FT 337 360 PF00096; zf-C2H2.
FT 337 360 SM00355; c2h2final6.
FT 337 365 PS50157; ZINC_FINGER_C2H2_2.
FT 339 360 zinc finger 4 [1].
FT 366 388 PF00096; zf-C2H2.
FT 366 388 SM00355; c2h2final6.
FT 366 393 PS50157; ZINC_FINGER_C2H2_2.
FT 368 388 zinc finger 5 [1].
FT 392 413 SM00355; c2h2final6.
FT 394 413 zinc finger 6 [1].
FT 419 442 PF00096; zf-C2H2.
FT 419 442 SM00355; c2h2final6.
FT 419 447 PS50157; ZINC_FINGER_C2H2_2.
FT 421 442 zinc finger 7 [1].
FT 452 474 SM00355; c2h2final6.
FT 454 474 zinc finger 8 [1].
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SF considered to be an alternative spliced form of the MAZ gene [1];
SF other splice variant is T00490 [1];
SF contain 8 zinc fingers of the C2H2-type [1];
SF suggested to form dimers with SAF-1, another splice variant of the MAZ gene [1];
SF phosphorylated by MAP kinase in vitro [1];
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FF level of transcript and protein decline during many inflammatory conditions [1];
FF its co-expression can considerably reduce the transactivation potential of MAZ/SAF-1 [1];
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MX M07297 V$MAZ_Q5.
MX M00649 V$MAZ_Q6.
MX M02023 V$MAZ_Q6_01.
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BS R12104.
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DR TRANSPATH: MO000056182.
DR EMBL: AF489858; AF489858.
DR UniProtKB: P56270-2; MAZ_HUMAN.
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RN [1]; RE0035146.
RX PUBMED: 12270922.
RA Ray B. K., Murphy R., Ray P., Ray A.
RT SAF-2, a splice variant of SAF-1, acts as a negative regulator of transcription.
RL J. Biol. Chem. 277:46822-46830 (2002).
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