AC T08303
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ID T08303
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DT 02.12.2005 (created); elf.
DT 06.05.2009 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA LRF-isoform2
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SY 9030619K07Rik; 9130006G12Rik; FBI-1; Leukemia/lymphoma related factor; Lrf; ZBTB7; zinc finger and BTB domain containing 7; Zinc finger and BTB domain containing protein 7A.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G021475 Zbtb7a.
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CL C0058; CH+BTB/POZ.
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SZ 565 AA; 59.8 kDa (cDNA) (calc.).
XX
SQ MAGGVDGPIGIPFPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFK
SQ KLFTSGAVVDQQNVYEIDFVSAEALTALMDFAYTATLTVSTANVGDILSAARLLEIPAVS
SQ HVCADLLERQILAADDVGDASQPDGAGPTDQRNLLRAKEYLEFFRSNPMNSLPPTAFPWS
SQ GFGAPDDDLDATKEAVAAAVAAVAAGDCNGLDFYGPGPPADRPPAGDGDEGDSTPGLWPE
SQ RDEDAPPGGLFPPPTAPPATTQNGHYGRAGAGTGEEEAAALSEAAPEPGDSPGFLSGAAE
SQ GEDGDAADVDGLAASTLLQQMMSSVGRAGDSDEESRTDDKGVMDYYLKYFSGAHEGDVYP
SQ AWSQKGEKKIRAKAFQKCPICEKVIQGAGKLPRHIRTHTGEKPYECNICKVRFTRQDKLK
SQ VHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHTGLRPYQCDSCCKTFVRSDHLHRHLK
SQ KDGCNGVPSRRGRKPRVRGVPPDVPAGAGAPPGLPDAPRNGQEKHFKDEEEASPDGSGRL
SQ NVAGSGGDDGAGGPAVATAEGNFAT
XX
SC translated from EMBL:AF086830
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FT 1 116 
POZ-domain [1].
FT 24 131 
PF00651; BTB/POZ domain.
FT 30 426 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 34 101 
PS50097; BTB.
FT 34 131 
SM00225; BTB_4.
FT 168 250 
proline-rich domain [1].
FT 376 398 
SM00355; c2h2final6.
FT 376 403 
PS50157; ZINC_FINGER_C2H2_2.
FT 378 454 
zinc finger 1,2,3 [1].
FT 404 426 
PF00096; zf-C2H2.
FT 404 426 SM00355; c2h2final6.
FT 404 431 PS50157; ZINC_FINGER_C2H2_2.
FT 432 454 PF00096; zf-C2H2.
FT 432 454 SM00355; c2h2final6.
FT 432 459 PS50157; ZINC_FINGER_C2H2_2.
FT 460 480 SM00355; c2h2final6.
FT 460 484 PF00096; zf-C2H2.
FT 460 495 PS50157; ZINC_FINGER_C2H2_2.
XX
IN T21852 HDAC1; Mammalia.
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MX M01100 V$LRF_Q2.
MX M07387 V$LRF_Q3.
MX M04617 V$LRF_Q6.
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BS R23816.
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DR TRANSPATH: MO000056598.
DR EMBL: AF086830; AF086830.
DR UniProtKB: O88939-2;
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RN [1]; RE0035587.
RX PUBMED: 10477728.
RA Kukita A., Kukita T., Ouchida M., Maeda H., Yatsuki H., Kohashi O.
RT Osteoclast-derived zinc finger (OCZF) protein with POZ domain, a possible transcriptional repressor, is involved in osteoclastogenesis.
RL Blood 94:1987-1997 (1999).
RN [2]; RE0047847.
RX PUBMED: 15337766.
RA Liu C. J., Prazak L., Fajardo M., Yu S., Tyagi N., Di Cesare P. E.
RT Leukemia/lymphoma-related factor, a POZ domain-containing transcriptional repressor, interacts with histone deacetylase-1 and inhibits cartilage oligomeric matrix protein gene expression and chondrogenesis.
RL J. Biol. Chem. 279:47081-47091 (2004).
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