AC T08490
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ID T08490
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DT 27.01.2006 (created); din.
DT 02.08.2013 (updated); yre.
CO Copyright (C), QIAGEN.
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FA MO15
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SY Cdk7; MO15; p39; p40; stk1; TFIIH-MO15.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004654 CDK7; HGNC: Cdk7.
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SZ 346 AA; 39.0 kDa (cDNA) (calc.).
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SQ MALDVKSRAKRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTAL
SQ REIKLLQELSHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLM
SQ TLQGLEYLHQHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRA
SQ PELLFGARMYGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDM
SQ CSLPDYVTFKSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPG
SQ PTPGCQLPRPNCPVETLKEQSNPALAIKRKRTEALEQGGLPKKLIF
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SC translated from EMBL:L20320
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FT 12 295 PF00069; Protein kinase domain.
FT 12 295 PS50011; PROTEIN_KINASE_DOM.
FT 12 295 SM00219; tyrkin_6.
FT 12 295 SM00220; serkin_6.
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IN T05299 NR1B1; human, Homo sapiens.
IN T08501 T3R-alpha; chick, Gallus gallus.
IN T08482 VDR-isoform1; human, Homo sapiens.
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DR TRANSPATH: MO000058865.
DR EMBL: L20320; HSSTK1A.
DR EMBL: X77743; HSCDKAK.
DR EMBL: X79193; HSCAKCDK.
DR UniProtKB: P50613;
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RN [1]; RE0017514.
RX PUBMED: 11584018.
RA Santaguida M., Ding Q., Berube G., Truscott M., Whyte P., Nepveu A.
RT Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2).
RL J. Biol. Chem. 276:45780-45790 (2001).
RN [2]; RE0047519.
RX PUBMED: 15249124.
RA Nevado J., Tenbaum S. P., Aranda A.
RT hSrb7, an essential human Mediator component, acts as a coactivator for the thyroid hormone receptor.
RL Mol. Cell. Endocrinol. 222:41-51 (2004).
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