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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T08493 XX ID T08493 XX DT 30.01.2006 (created); res. DT 11.03.2010 (updated); jig. CO Copyright (C), QIAGEN. XX FA c-Fos XX SY c-Fos; FBJ osteosarcoma oncogene. XX OS rat, Rattus norvegicus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G002143 Fos. XX CL C0008; bZIP. XX SZ 380 AA; 40.9 kDa (cDNA) (calc.), 55-65 kDa (SDS) XX SQ MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANF SQ IPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTPSTGAYARAGVVKTMSGGRA SQ QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQ SQ TEIANLLKEKEKLEFILAAHRPACKIPNDLGFPEEMSVTSLDLTGGLPEATTPESEEAFT SQ LPLLNDPEPKPSLEPVKNISNMELKAEPFDDFLFPASSRPSGSETARSVPDVDLSGSFYA SQ ADWEPLHSSSLGMGPMVTELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCAAAHRK SQ GSSSNEPSSDSLSSPTLLAL XX SC Swiss-Prot#P12841 XX FT 1 47 transcription activation module FAM1 [8]. FT 47 81 transcription activation module FAM2 [8]. FT 63 74 HOB1-N [8]. FT 81 142 inhibitory domain ID1 containing inhibitory motif IM1 (GRRGK) [8]. FT 135 199 PF00170; bZIP transcription factor. FT 135 199 SM00338; brlzneu. FT 137 200 PS50217; BZIP. FT 210 244 transcription activation module FAM3 [8]. FT 244 308 transcription activation module FAM4 [8]. FT 267 276 HOB2 [9]. FT 308 380 transcription activation module FAM5 [8]. XX IN T08466 c-Jun; rat, Rattus norvegicus. IN T08587 c-Jun; mouse, Mus musculus. IN T23077 CHOP-10; Mammalia. IN T08590 JunB; mouse, Mus musculus. IN T08536 JunD; mouse, Mus musculus. XX MX M00172 V$AP1FJ_Q2. MX M00517 V$AP1_01. MX M00924 V$AP1_Q2_01. MX M00926 V$AP1_Q4_01. MX M00925 V$AP1_Q6_01. MX M03815 V$CFOS_Q6. XX BS R08094. BS R05033. BS R05083. BS R05089. BS R05091. BS R05093. BS R05035. BS R05071. BS R04330. XX DR TRANSPATH: MO000058978. DR EMBL: U02631; DR EMBL: X06769; DR UniProtKB: P12841; XX RN [1]; RE0016689. RX PUBMED: 7648395. RA Bassuk A. G., Leiden J. M. RT A direct physical association between ETS and AP-1 transcription factors in normal human T cells. RL Immunity 3:223-237 (1995). RN [2]; RE0046520. RX PUBMED: 10567391. RA Kabe Y., Goto M., Shima D., Imai T., Wada T., Morohashi K., Shirakawa M., Hirose S., Handa H. RT The role of human MBF1 as a transcriptional coactivator RL J. Biol. Chem. 274:34196-202 (1999). RN [3]; RE0047533. RX PUBMED: 10523647. RA Ubeda M., Vallejo M., Habener J. F. RT CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins. RL Mol. Cell. Biol. 19:7589-7599 (1999). RN [4]; RE0047872. RX PUBMED: 9685505. RA Yamaguchi Y., Wada T., Suzuki F., Takagi T., Hasegawa J., Handa H. RT Casein kinase II interacts with the bZIP domains of several transcription factors. RL Nucleic Acids Res. 26:3854-3861 (1998). RN [5]; RE0049305. RX PUBMED: 16055710. RA Bossis G., Malnou C. E., Farras R., Andermarcher E., Hipskind R., Rodriguez M., Schmidt D., Muller S., Jariel-Encontre I., Piechaczyk M. RT Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation. RL Mol. Cell. Biol. 25:6964-6979 (2005). RN [6]; RE0054068. RX PUBMED: 11925568. RA Zhang J., Zhang D., McQuade J. S., Behbehani M., Tsien J. Z., Xu M. RT c-fos regulates neuronal excitability and survival. RL Nat. Genet. 30:416-420 (2002). RN [7]; RE0066145. RX PUBMED: 20053986. RA Malnou C. E., Brockly F., Favard C., Moquet-Torcy G., Piechaczyk M., Jariel-Encontre I. RT Heterodimerization with different Jun proteins controls c-Fos intranuclear dynamics and distribution. RL J. Biol. Chem. 285:6552-6562 (2010). RN [8]; RE0004823. RX PUBMED: 7828584. RA Brown H. J., Sutherland J. A., Cook A., Bannister A. J., Kouzarides T. RT An inhibitor domain in c-Fos regulates activation domains containing the HOB1 motif RL EMBO J. 14:124-131 (1995). RN [9]; RE0004818. RX PUBMED: 1516835. RA Sutherland J. A., Cook A., Bannister A. J., Kouzarides T. RT Conserved motifs in Fos and Jun define a new class of activation domain RL Genes Dev. 6:1810-1819 (1992). XX //