AC T08639
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ID T08639
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DT 08.03.2006 (created); man.
DT 23.11.2007 (updated); jag.
CO Copyright (C), QIAGEN.
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FA PPARgamma
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SY NR1C3; peroxisome proliferator-activated receptor gamma; PPARgamma.
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OS clawed frog, Xenopus laevis
OC eukaryota; animalia; metazoa; chordata; vertebrata; amphibia; lissamphibia; anura; archeobatrachia; pipoidea; pipidae
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GE G031449 pparg.L.
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CL C0002; CC (rec).
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SZ 477 AA; 54.1 kDa (cDNA) (calc.).
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SQ MVDTEMPFWSNLNFGMNSMDMSALEDHCQPYDIKPFTTVDFSSINSHYDDILDEKTFLCR
SQ NDQSPIDYKYDLKLQECQSSIKLEPPSPPYFSDKPQCSKAFEDTPNSFIAIECRVCGDKA
SQ SGFHYGVHACEGCKGFFRRTIRLKLIYERCDLNCRIHKKSRNKCQFCRFQKCLAVGMSHN
SQ AIRFGRMPQAEKEKLLAEISSDIDQLNPESADQRVLAKHLYDSYVKSFPLTKAKAPGHPD
SQ GQSHRQNSRGYTRHELADDGGGSDQGAVREPRAEQGGGDSNLPALSVALRGGVREITEFA
SQ KNIPGFVSLDLNDQVTLLKYGVHEIIFTMLASLMNKDGVLVAEGQGFMTREFLKSLRKPF
SQ SDFMEPKFEFAIRFNSLELDDSDLAIFVAVIILSGDRPGLLNVKPIEDIQDSLLQALELQ
SQ LKLNHPDSAQLFAKLLQKMTDLRQVVTEHVQLLQLIKKTEADMCLHPLLQEIYKDLY
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SC Swiss-Prot#P37234
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FT 50 352 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 85 88 
consensus MAP kinase site [2].
FT 110 180 
SM00399; c4gold.
FT 110 184 
PS51030; NUCLEAR_REC_DBD_2.
FT 111 185 
PF00105; Zinc finger, C4 type (two domains).
FT 112 177 
DNA-binding domain [3].
FT 284 477 
ligand-binding domain [3].
FT 287 446 
SM00430; holi.
FT 290 472 
PF00104; Ligand-binding domain of nuclear hormon.
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IN T01516 Pit-1B; rat, Rattus norvegicus.
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MX M00763 V$PPARDR1_Q2.
MX M00512 V$PPARG_01.
MX M00515 V$PPARG_02.
MX M00528 V$PPARG_03.
MX M01270 V$PPARG_Q6.
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BS R11727.
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DR TRANSPATH: MO000078825.
DR EMBL: M84163;
DR UniProtKB: P37234;
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RN [1]; RE0049967.
RX PUBMED: 9113987.
RA Kliewer S. A., Sundseth S. S., Jones S. A., Brown P. J., Wisely G. B., Koble C. S., Devchand P., Wahli W., Willson T. M., Lenhard J. M., Lehmann J. M.
RT Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma.
RL Proc. Natl. Acad. Sci. USA 94:4318-4323 (1997).
RN [2]; RE0018160.
RX PUBMED: 9030579.
RA Adams M., Reginato M. J., Shao D., Lazar M. A., Chatterjee V. K.
RT Transcriptional activation by peroxisome proliferator-activated receptor gamma is inhibited by phosphorylation at a consensus mitogen-activated protein kinase site.
RL J. Biol. Chem. 272:5128-5132 (1997).
RN [3]; RE0018281.
RX PUBMED: 8041794.
RA Kliewer S. A., Forman B. M., Blumberg B., Ong E. S., Borgmeyer U., Mangelsdorf D. J., Umesono K., Evans R. M.
RT Differential expression and activation of a family of murine peroxisome proliferator-activated receptors.
RL Proc. Natl. Acad. Sci. USA 91:7355-7359 (1994).
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