AC T08770
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ID T08770
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DT 29.03.2006 (created); sla.
DT 10.05.2012 (updated); sla.
CO Copyright (C), QIAGEN.
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FA PDX-1
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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CL C0006; homeo.
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FF the C-terminal sequences of p300 interacts with the N-terminal activation domain region of PDX-1 [1];
FF PDX-1 activation is enhanced by p300 and stimulated synergistically in conjunction with the BETA2:E47 complex the insulin gene transcription activation [1];
FF E1A also inhibited PDX-1 activation through binding to p300 [1];
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IN T02003 Cdx-3; golden (Syrian) hamster, Mesocricetus auratus.
IN T09257 pax-6; quail, Coturnix coturnix.
IN T14852 Pax-6; hamster, Cricetulus sp.
IN T08770 PDX-1; Mammalia.
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BS R19506.
BS R19509.
BS R19507.
BS R19508.
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DR TRANSPATH: MO000079665.
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RN [1]; RE0041701.
RX PUBMED: 11756538.
RA Qiu Y., Guo M., Huang S., Stein R.
RT Insulin gene transcription is mediated by interactions between the p300 coactivator and PDX-1, BETA2, and E47
RL Mol. Cell. Biol. 22:412-20 (2002).
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