AC T08814
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ID T08814
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DT 07.04.2006 (created); jay.
DT 10.10.2011 (updated); sla.
CO Copyright (C), QIAGEN.
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FA TEL1
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SY ETS translocation variant 6; ETS-related protein Tel1; ETV6; tel; Transcription factor ETV6.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G006041 ETV6; HGNC: ETV6.
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CL C0016; ETS.
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SZ 452 AA; 53.0 kDa (cDNA) (calc.).
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SQ MSETPAQCSIKQERISYTPPESPVPSYASSTPLHVPVPRALRMEEDSIRLPAHLRLQPIY
SQ WSRDDVAQWLKWAENEFSLRPIDSNTFEMNGKALLLLTKEDFRYRSPHSGDVLYELLQHI
SQ LKQRKPRILFSPFFHPGNSIHTQPEVILHQNHEEDNCVQRTPRPSVDNVHHNPPTIELLH
SQ RSRSPITTNHRPSPDPEQRPLRSPLDNMIRRLSPAERAQGPRPHQENNHQESYPLSVSPM
SQ ENNHCPASSESHPKPSSPRQESTRVIQLMPSPIMHPLILNPRHSVDFKQSRLSEDGLHRE
SQ GKPINLSHREDLAYMNHIMVSVSPPEEHAMPIGRIADCRLLWDYVYQLLSDSRYENFIRW
SQ EDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRALRHYYKLNIIRKEPGQRLLFRFM
SQ KTPDEIMSGRTDRLEHLESQELDEQIYQEDEC
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SC Swiss-Prot#P41212
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FT 1 154 
present in the Tel-PDGFbeta chimeric protein [1].
FT 38 124 
PF02198; Sterile alpha motif (SAM)/Pointed domain.
FT 38 124 
SM00251; SAM2_3.
FT 46 127 
interactions with STAT3, repression of STAT3 transcriptional activity [2].
FT 57 124 
POINTED domain of homology [1].
FT 338 422 
PF00178; Ets-domain.
FT 338 424 
SM00413; etsneu2.
FT 339 420 
PS50061; ETS_DOMAIN_3.
FT 341 410 
PS50140; HSF_ETS.
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IN T14458 STAT3; Mammalia.
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MX M02070 V$TEL1_02.
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BS R26849.
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DR TRANSPATH: MO000079982.
DR TRANSCOMPEL: C00483.
DR EMBL: U11732;
DR UniProtKB: P41212;
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RN [1]; RE0000282.
RX PUBMED: 8168137.
RA Golub T. R., Barker G. F., Lovett M., Gilliland D. G.
RT Fusion of PDGf receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
RL Cell 77:307-316 (1994).
RN [2]; RE0047428.
RX PUBMED: 15229229.
RA Schick N., Oakeley E. J., Hynes N. E., Badache A.
RT TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity.
RL J. Biol. Chem. 279:38787-38796 (2004).
RN [3]; RE0052481.
RX PUBMED: 12590135.
RA Petrie K., Guidez F., Howell L., Healy L., Waxman S., Greaves M., Zelent A.
RT The histone deacetylase 9 gene encodes multiple protein isoforms.
RL J. Biol. Chem. 278:16059-16072 (2003).
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